thalidomide has been researched along with Erythema Multiforme in 20 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Erythema Multiforme: A skin and mucous membrane disease characterized by an eruption of macules, papules, nodules, vesicles, and/or bullae with characteristic bull's-eye lesions usually occurring on the dorsal aspect of the hands and forearms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recurrent erythema multiforme is a rare disorder, clinically characterized by symmetrically distributed, erythematous, and bullous skin and mucous lesions, mainly precipitated by a preceding herpes simplex infection." | 6.42 | Thalidomide as elective treatment in persistent erythema multiforme; report of two cases. ( Conejo-Mir, JS; del Canto, S; Hernandez, C; Muñoz, MA; Pulpillo, A; Rodríguez-Freire, L; Serrano, A, 2003) |
| "Erythema multiforme is a common self-limited disorder that predominantly affects younger individuals." | 5.35 | Persistent erythema multiforme treated with thalidomide. ( Chen, CW; Chen, YF; Hung, CM; Tsai, TF, 2008) |
| "The objective of this study was to evaluate the efficacy of thalidomide in the treatment of chronic erythema multiforme unresponsive to usual treatments." | 3.69 | [Treatment by thalidomide of chronic multiforme erythema: its recurrent and continuous variants. A retrospective study of 26 patients]. ( Cambazard, F; Cherouati, K; Claudy, A; Crickx, B; Lamorelle, A; Morel, P; Moulin, G; Revuz, J; Souteyrand, P; Vaillant, L, 1996) |
| "We report a case of a 23-year-old woman who was afflicted with disseminated skin erythema multiforme-like eruptions that started at the menarche, relapsed at the premenstrual periods, dramatically spread during two pregnancies and cleared after abortion; the skin lesions responded dramatically to thalidomide treatment." | 3.68 | Erythema multiforme associated with autoreactivity to 17 alpha-hydroxyprogesterone. ( Arala-Chaves, M; Baló-Banga, M; da Silva, MB; Pinto, JS; Porto, MT; Santos, MA; Sobrinho, L, 1990) |
| "Recognition and timely adequate treatment of erythema multiforme remain a major challenge." | 2.58 | Current Perspectives on Erythema Multiforme. ( Harr, T; Lerch, M; Mainetti, C; Terziroli Beretta-Piccoli, B, 2018) |
| "Recurrent erythema multiforme is a rare disorder, clinically characterized by symmetrically distributed, erythematous, and bullous skin and mucous lesions, mainly precipitated by a preceding herpes simplex infection." | 2.42 | Thalidomide as elective treatment in persistent erythema multiforme; report of two cases. ( Conejo-Mir, JS; del Canto, S; Hernandez, C; Muñoz, MA; Pulpillo, A; Rodríguez-Freire, L; Serrano, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roux, C | 1 |
| Sbidian, E | 1 |
| Bouaziz, JD | 1 |
| Kottler, D | 1 |
| Joly, P | 1 |
| Descamps, V | 1 |
| Prost, C | 1 |
| Samimi, M | 1 |
| Seneschal, J | 1 |
| Dupin, N | 1 |
| Girard, C | 1 |
| Paul, M | 1 |
| Le Cleach, L | 1 |
| Ingen-Housz-Oro, S | 2 |
| Chen, T | 1 |
| Levitt, J | 1 |
| Geller, L | 1 |
| Lerch, M | 1 |
| Mainetti, C | 1 |
| Terziroli Beretta-Piccoli, B | 1 |
| Harr, T | 1 |
| Drahy, F | 1 |
| Grootenboer-Mignot, S | 1 |
| Wolkenstein, P | 1 |
| Chosidow, O | 1 |
| Aslam, A | 1 |
| Chalmers, R | 1 |
| Castaneda, CP | 1 |
| Brandenburg, NA | 1 |
| Bwire, R | 1 |
| Burton, GH | 1 |
| Zeldis, JB | 1 |
| Conejo-Mir, JS | 1 |
| del Canto, S | 1 |
| Muñoz, MA | 1 |
| Rodríguez-Freire, L | 1 |
| Serrano, A | 1 |
| Hernandez, C | 1 |
| Pulpillo, A | 1 |
| Varma, K | 1 |
| Finlay, AY | 1 |
| Chen, CW | 1 |
| Tsai, TF | 1 |
| Chen, YF | 1 |
| Hung, CM | 1 |
| Bahmer, FA | 1 |
| Zaun, H | 1 |
| Luszpinski, P | 1 |
| Cherouati, K | 1 |
| Claudy, A | 1 |
| Souteyrand, P | 1 |
| Cambazard, F | 1 |
| Vaillant, L | 1 |
| Moulin, G | 1 |
| Crickx, B | 1 |
| Morel, P | 1 |
| Lamorelle, A | 1 |
| Revuz, J | 2 |
| Engeser, P | 1 |
| Klimm, HD | 1 |
| Saano, V | 1 |
| Alonso, AM | 1 |
| Moisson, YF | 1 |
| Janier, M | 1 |
| Civatte, J | 1 |
| Pinto, JS | 1 |
| Sobrinho, L | 1 |
| da Silva, MB | 1 |
| Porto, MT | 1 |
| Santos, MA | 1 |
| Baló-Banga, M | 1 |
| Arala-Chaves, M | 1 |
| Naafs, B | 1 |
| Faber, WR | 1 |
| Opromolla, DV | 1 |
| Lima, LS | 1 |
| Marques, MB | 1 |
| Duperrat, B | 1 |
| Puissant, A | 1 |
| Pringuet, R | 1 |
| Lauret, P | 1 |
| Baccaredda-Boy, A | 1 |
| Bertamino, R | 1 |
3 reviews available for thalidomide and Erythema Multiforme
| Article | Year |
|---|---|
Current Perspectives on Erythema Multiforme.
Topics: Acyclovir; Dapsone; Drug-Related Side Effects and Adverse Reactions; Erythema Multiforme; Herpes Sim | 2018 |
Thalidomide as elective treatment in persistent erythema multiforme; report of two cases.
Topics: Adult; Epstein-Barr Virus Infections; Erythema Multiforme; Female; Humans; Middle Aged; Thalidomide | 2003 |
[New therapeutic application of thalidomide].
Topics: Autoimmune Diseases; Colitis, Ulcerative; Erythema Multiforme; Female; Histiocytosis; Humans; Immuno | 1996 |
1 trial available for thalidomide and Erythema Multiforme
| Article | Year |
|---|---|
[Thalidomide in acute symptoms in leprosy (erythema nodosum or multiforme)].
Topics: Clinical Trials as Topic; Erythema Multiforme; Erythema Nodosum; Female; Humans; Lepromin; Leprosy; | 1966 |
16 other studies available for thalidomide and Erythema Multiforme
| Article | Year |
|---|---|
Evaluation of Thalidomide Treatment of Patients With Chronic Erythema Multiforme: A Multicenter Retrospective Cohort Study.
Topics: Adolescent; Adult; Cohort Studies; Erythema Multiforme; Female; Humans; Remission Induction; Retrosp | 2021 |
Apremilast for treatment of recurrent erythema multiforme.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Erythema Multiforme; Female; Humans; Male; Mo | 2017 |
Lenalidomide as an Alternative to Thalidomide for Treatment of Recurrent Erythema Multiforme.
Topics: Adult; Chronic Disease; Drug Substitution; Erythema Multiforme; Female; Humans; Immunologic Factors; | 2018 |
Mucocutaneous ulceration in a previously healthy man.
Topics: Adult; Behcet Syndrome; Crohn Disease; Diagnosis, Differential; Erythema Multiforme; Herpes Simplex; | 2014 |
Erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis in lenalidomide-treated patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Erythema Multiforme; Female; Humans; Lenalidomide; M | 2009 |
Exacerbation of psoriasis by thalidomide in a patient with erythema multiforme.
Topics: Adult; Drug Eruptions; Erythema Multiforme; Female; Humans; Immunosuppressive Agents; Psoriasis; Tha | 2006 |
Persistent erythema multiforme treated with thalidomide.
Topics: Adolescent; Erythema Multiforme; Humans; Immunosuppressive Agents; Male; Skin; Thalidomide | 2008 |
Thalidomide treatment of recurrent erythema multiforme.
Topics: Adult; Erythema Multiforme; Humans; Male; Neurologic Examination; Recurrence; Thalidomide | 1982 |
[Treatment by thalidomide of chronic multiforme erythema: its recurrent and continuous variants. A retrospective study of 26 patients].
Topics: Adolescent; Adult; Aged; Chronic Disease; Erythema Multiforme; Female; Humans; Immunosuppressive Age | 1996 |
[Therapy of recurrent exudative erythema multiforme. Effectiveness of thalidomide--report of a case].
Topics: Aged; Dermatologic Agents; Erythema Multiforme; Female; Humans; Recurrence; Thalidomide; Treatment O | 1999 |
[Reactional status of leprosy].
Topics: Erythema Multiforme; Erythema Nodosum; Humans; Thalidomide; Tuberculoma | 1975 |
Thalidomide for recurrent erythema multiforme.
Topics: Adult; Erythema Multiforme; Humans; Male; Thalidomide | 1992 |
Erythema multiforme associated with autoreactivity to 17 alpha-hydroxyprogesterone.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Erythema Multiforme; Female; HLA Antigens; Humans; Hydroxyproge | 1990 |
Thalidomide therapy. An open trial.
Topics: Adult; Aged; Central Nervous System Diseases; Erythema Multiforme; Female; Humans; Lichen Planus; Lu | 1985 |
[Failure of thalidomide treatment in a case of leprous erythema multiforme].
Topics: Adult; Erythema Multiforme; Humans; Leprosy; Male; Sulfamethoxypyridazine; Thalidomide | 1968 |
[Our experience in the therapy of leprous reactions with thalidomide].
Topics: Erythema Multiforme; Erythema Nodosum; Humans; Leprosy; Thalidomide | 1968 |