thalidomide has been researched along with Episcleritis in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lenalidomide is an immunomodulatory agent that was approved for the treatment of a monoclonal bone marrow disorders, myelodysplastic syndrome del(5q)(MDS del(5q)), in 2005; the drug was subsequently also approved for the treatment of refractory multiple myeloma, a bone marrow malignancy of the B-lymphocyte lineage." | 5.39 | Can lenalidomide play a role in the management of scleritis? ( Abul, N; Al-Awadhi, A; Al-Jafar, HA; Kumar, N, 2013) |
| "Lenalidomide is an immunomodulatory agent that was approved for the treatment of a monoclonal bone marrow disorders, myelodysplastic syndrome del(5q)(MDS del(5q)), in 2005; the drug was subsequently also approved for the treatment of refractory multiple myeloma, a bone marrow malignancy of the B-lymphocyte lineage." | 1.39 | Can lenalidomide play a role in the management of scleritis? ( Abul, N; Al-Awadhi, A; Al-Jafar, HA; Kumar, N, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Jafar, HA | 1 |
| Abul, N | 1 |
| Kumar, N | 1 |
| Al-Awadhi, A | 1 |
| Huddleston, SM | 1 |
| Houser, KH | 1 |
| Walton, RC | 1 |
2 other studies available for thalidomide and Episcleritis
| Article | Year |
|---|---|
Can lenalidomide play a role in the management of scleritis?
Topics: Female; Humans; Immunologic Factors; Lenalidomide; Middle Aged; Scleritis; Thalidomide | 2013 |
Thalidomide for recalcitrant nodular scleritis in sarcoidosis.
Topics: Female; Humans; Immunosuppressive Agents; Middle Aged; Recurrence; Sarcoidosis; Scleritis; Thalidomi | 2014 |