thalidomide has been researched along with Epidermolysis Bullosa in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Epidermolysis Bullosa: Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strauss, RM | 1 |
| Bäte, J | 1 |
| Nischal, KK | 1 |
| Clayton, T | 1 |
| Gooi, J | 1 |
| Darling, JC | 1 |
| Newton-Bishop, JA | 1 |
1 other study available for thalidomide and Epidermolysis Bullosa
| Article | Year |
|---|---|
A child with laryngo-onychocutaneous syndrome partially responsive to treatment with thalidomide.
Topics: Adolescent; Conjunctival Diseases; Epidermolysis Bullosa; Female; Humans; Immunosuppressive Agents; | 2006 |