thalidomide has been researched along with Endometrioma in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thalidomide proved to be effective in reducing the lesion area and CPI of the experimental endometriosis implants both at the dose of 1 mg/kg/day and at the dose of 10 mg/kg/day." | 7.91 | Thalidomide Reduces Cell Proliferation in Endometriosis Experimentally Induced in Rats. ( Antônio, LGL; Candido-Dos-Reis, FJ; Garcia, SB; Machado, DJ; Nogueira, AA; Poli-Neto, OB; Rosa-E-Silva, JC; Westin, AT, 2019) |
| "This study aimed to assess the efficacy of thalidomide for treatment of experimental endometriosis." | 7.80 | Thalidomide affects experimental endometriosis: a randomized controlled study in the rat. ( Alborzi, S; Azimirad, A; Azimirad, M; Kumar, PV; Tavana, Z; Zarei, A; Zolghadri, J, 2014) |
| " Thalidomide proved to be effective in reducing the lesion area and CPI of the experimental endometriosis implants both at the dose of 1 mg/kg/day and at the dose of 10 mg/kg/day." | 3.91 | Thalidomide Reduces Cell Proliferation in Endometriosis Experimentally Induced in Rats. ( Antônio, LGL; Candido-Dos-Reis, FJ; Garcia, SB; Machado, DJ; Nogueira, AA; Poli-Neto, OB; Rosa-E-Silva, JC; Westin, AT, 2019) |
| "This study aimed to assess the efficacy of thalidomide for treatment of experimental endometriosis." | 3.80 | Thalidomide affects experimental endometriosis: a randomized controlled study in the rat. ( Alborzi, S; Azimirad, A; Azimirad, M; Kumar, PV; Tavana, Z; Zarei, A; Zolghadri, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antônio, LGL | 1 |
| Rosa-E-Silva, JC | 1 |
| Machado, DJ | 1 |
| Westin, AT | 1 |
| Garcia, SB | 1 |
| Candido-Dos-Reis, FJ | 1 |
| Poli-Neto, OB | 1 |
| Nogueira, AA | 1 |
| Azimirad, A | 1 |
| Alborzi, S | 1 |
| Kumar, PV | 1 |
| Zolghadri, J | 1 |
| Zarei, A | 1 |
| Tavana, Z | 1 |
| Azimirad, M | 1 |
| Yagyu, T | 1 |
| Kobayashi, H | 1 |
| Matsuzaki, H | 1 |
| Wakahara, K | 1 |
| Kondo, T | 1 |
| Kurita, N | 1 |
| Sekino, H | 1 |
| Inagaki, K | 1 |
| Suzuki, M | 1 |
| Kanayama, N | 1 |
| Terao, T | 1 |
3 other studies available for thalidomide and Endometrioma
| Article | Year |
|---|---|
Thalidomide Reduces Cell Proliferation in Endometriosis Experimentally Induced in Rats.
Topics: Angiogenesis Inhibitors; Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Dose-Respo | 2019 |
Thalidomide affects experimental endometriosis: a randomized controlled study in the rat.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Endometriosis; Female; Immunosuppressive A | 2014 |
Thalidomide inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endometriotic stromal cells, possibly through suppression of nuclear factor-kappaB activation.
Topics: Active Transport, Cell Nucleus; Cells, Cultured; Endometriosis; Female; Humans; I-kappa B Proteins; | 2005 |