thalidomide has been researched along with Endocrine System Diseases in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Endocrine System Diseases: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide is a synthetic glutamic acid derivative first introduced in 1956 in Germany as an over the counter medications." | 2.50 | [Current therapeutic indications of thalidomide and lenalidomide]. ( Cosiglio, FJ; Ordi-Ros, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ordi-Ros, J | 1 |
| Cosiglio, FJ | 1 |
| KOPF, R | 1 |
| LORENZ, D | 1 |
| SALEWSKI, E | 1 |
| DE JONGE, GA | 1 |
| Getty, J | 1 |
| Grunfeld, C | 1 |
| Homburger, F | 1 |
| Bajusz, E | 1 |
1 review available for thalidomide and Endocrine System Diseases
| Article | Year |
|---|---|
[Current therapeutic indications of thalidomide and lenalidomide].
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents; Antineoplastic Agents; Collagen Diseases; End | 2014 |
5 other studies available for thalidomide and Endocrine System Diseases
| Article | Year |
|---|---|
[THE EFFECT OF THALIDOMIDE ON THE FERTILITY OF RATS IN REPRODUCTION EXPERIMENTS OVER 2 GENERATIONS].
Topics: Endocrine System Diseases; Fertility; Pharmacology; Pregnancy; Pregnancy, Animal; Rats; Reproduction | 1964 |
[FETAL DAMAGE CAUSED BY PHARMACEUTICAL AGENTS].
Topics: Abnormalities, Drug-Induced; Endocrine System Diseases; Fetal Diseases; Humans; Morphine Dependence; | 1965 |
Turning the corner on wasting? A symposium on wasting disorders.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cachexia; Endocrine System Diseases; Humans; M | 1995 |
State of the art in wasting: an interview with Carl Grunfeld, PhD. Interview by Jeff Getty.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Animals; Cachexia; Endocr | 1995 |
New models of human disease in Syrian hamsters.
Topics: Adenoma; Adrenal Gland Neoplasms; Animals; Cardiomyopathies; Cricetinae; Cyclamates; Disease Models, | 1970 |