thalidomide has been researched along with Encephalitis in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide (TAL) has shown potential therapeutic effects in neurological diseases like epilepsy." | 5.91 | Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model. ( Cumbres-Vargas, IM; Pichardo-Macías, LA; Ramírez-San Juan, E; Zamudio, SR, 2023) |
| "Thalidomide (TAL) has shown potential therapeutic effects in neurological diseases like epilepsy." | 1.91 | Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model. ( Cumbres-Vargas, IM; Pichardo-Macías, LA; Ramírez-San Juan, E; Zamudio, SR, 2023) |
| "Frequency and intensity of epileptic seizures were reduced significantly, and the quality of her life improved." | 1.32 | Rasmussen syndrome and long-term response to thalidomide. ( Djordjevic, MS; Kravljanac, RM; Marjanovic, BD; Stojanov, LM; Zdravkovic, DS, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cumbres-Vargas, IM | 1 |
| Zamudio, SR | 1 |
| Pichardo-Macías, LA | 1 |
| Ramírez-San Juan, E | 1 |
| Lin, CT | 1 |
| Lecca, D | 1 |
| Yang, LY | 1 |
| Luo, W | 3 |
| Scerba, MT | 1 |
| Tweedie, D | 4 |
| Huang, PS | 1 |
| Jung, YJ | 1 |
| Kim, DS | 1 |
| Yang, CH | 1 |
| Hoffer, BJ | 2 |
| Wang, JY | 3 |
| Greig, NH | 4 |
| Yoon, JS | 1 |
| Lee, JH | 1 |
| Mughal, MR | 1 |
| Chigurupati, S | 1 |
| Mattson, MP | 1 |
| Huang, YN | 1 |
| Chiu, CC | 1 |
| Pick, CG | 1 |
| Chou, SY | 1 |
| Luo, Y | 1 |
| Belarbi, K | 1 |
| Jopson, T | 1 |
| Arellano, C | 1 |
| Rosi, S | 1 |
| Marjanovic, BD | 1 |
| Stojanov, LM | 1 |
| Zdravkovic, DS | 1 |
| Kravljanac, RM | 1 |
| Djordjevic, MS | 1 |
6 other studies available for thalidomide and Encephalitis
| Article | Year |
|---|---|
Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model.
Topics: Animals; Disease Models, Animal; Encephalitis; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Male; | 2023 |
3,6'-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation.
Topics: Animals; Brain Injuries; Cytokines; Encephalitis; Male; Mice; Mice, Inbred C57BL; Microglia; Neurons | 2020 |
3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Infarction; Cell Death; Cytokines; Dis | 2013 |
Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat.
Topics: Animals; Apoptosis; Brain Injuries, Traumatic; Cells, Cultured; Cerebral Cortex; Cytokines; Disease | 2016 |
TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation.
Topics: Analysis of Variance; Animals; Apoptosis Regulatory Proteins; Cognition Disorders; Disease Models, A | 2012 |
Rasmussen syndrome and long-term response to thalidomide.
Topics: Adolescent; Anticonvulsants; Brain; Electroencephalography; Encephalitis; Female; Humans; Magnetic R | 2003 |