thalidomide has been researched along with Embryopathies in 108 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to show the frequency, localisation, intensity, quality and degree of chronic pain in people with thalidomide-induced congenital defects (thalidomide embryopathy) and to investigate the association with biopsychosocial factors more closely." | 8.02 | [Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors]. ( Albus, C; Lüngen, M; Niecke, A; Peters, KM; Pfaff, H; Ramesh, I; Samel, C, 2021) |
| "40 000 new cases of leprosy are diagnosed every year in Brazil." | 6.49 | Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings. ( da Costa, LMM; de Sousa, SHC; Dias, MF; Doriqui, MJR; Leite, JCL; Maximino, CM; Morelo, EF; Sanseverino, MTV; Schüler-Faccini, L; Vianna, FSL, 2013) |
| "Thalidomide (TD) displays remarkable species specificity, causing birth defects (teratogenesis) in humans and rabbits, but not rats or mice; yet, few determinants of species susceptibility have been identified." | 5.37 | Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture. ( Gonçalves, LL; Lee, CJ; Wells, PG, 2011) |
| "As individuals with thalidomide embryopathy now reaching their 60's they undergo long-term sequelae of their prenatal damage and experience a wide range of secondary health problems, in particular chronic musculoskeletal pain, movement restrictions, and mental disorders." | 4.12 | Health-related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross-sectional survey. ( Alayli, A; Albus, C; Lüngen, M; Niecke, A; Peters, KM; Pfaff, H; Samel, C, 2022) |
| "The aim of the study was to show the frequency, localisation, intensity, quality and degree of chronic pain in people with thalidomide-induced congenital defects (thalidomide embryopathy) and to investigate the association with biopsychosocial factors more closely." | 4.02 | [Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors]. ( Albus, C; Lüngen, M; Niecke, A; Peters, KM; Pfaff, H; Ramesh, I; Samel, C, 2021) |
| "A case of thalidomide syndrome diagnosed by ultrasound in the 17th week of pregnancy is presented." | 3.67 | Prenatal diagnosis of thalidomide syndrome. ( Eigier, A; Gollop, TR; Guidugli Neto, J, 1987) |
| " Animal models of hemifacial microsomia and thalidomide-induced otomandibular dysostosis are described; the causal mechanism of malformation appeared to be closely related to the formation of a hematoma at the time of development of the stapedial arterial systems." | 3.65 | Hemorrhage in development of the face. ( Poswillo, D, 1975) |
| "40 000 new cases of leprosy are diagnosed every year in Brazil." | 2.49 | Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings. ( da Costa, LMM; de Sousa, SHC; Dias, MF; Doriqui, MJR; Leite, JCL; Maximino, CM; Morelo, EF; Sanseverino, MTV; Schüler-Faccini, L; Vianna, FSL, 2013) |
| "Present knowledge of chromosomal aberrations associated with microphthalmia is surveyed, and some of the syndromes and phenocopies in the mentally retarded in which microphthalmia may be found are reviewed." | 2.35 | The heterogeneity of microphthalmia in the mentally retarded. ( Warburg, M, 1971) |
| "Thirty-three patients (26%) reported neuropathic pain." | 1.91 | Age-related changes in patients with upper limb thalidomide embryopathy in the United Kingdom. ( Brennan, S; Hooper, G; Lam, W; Markiewicz, M; Stirling, P, 2023) |
| "Thalidomide is a drug responsible to a spectrum of congenital anomalies known as Thalidomide Embryopathy (TE), which includes mainly limb and heart defects." | 1.72 | Genetic evaluation of HAND2 gene and its effects on thalidomide embryopathy. ( Bremm, JM; do Amaral Gomes, J; Fraga, LR; Kowalski, TW; Rengel, BD; Schüler-Faccini, L; Vianna, FSL, 2022) |
| "Thalidomide was used as a sedative drug for pregnant women in the 1950-60:s and resulted in children born with thalidomide embryopathy (TE), including upper limb malformations." | 1.43 | Degenerative Changes in the Cervical Spine Are More Common in Middle-Aged Individuals with Thalidomide Embryopathy than in Healthy Controls. ( Ab-Fawaz, R; Brisby, H; Danielson, B; Danielsson, A; Ghassemi Jahani, SA; Hebelka, H, 2016) |
| "Thalidomide is a known teratogen and it is estimated that more than ten thousand babies were affected by thalidomide embryopathy (TE), which is characterized mainly by limb defects, but can involve many organs and systems." | 1.42 | Thalidomide embryopathy: Follow-up of cases born between 1959 and 2010. ( Kowalski, TW; Sanseverino, MT; Schuler-Faccini, L; Vianna, FS, 2015) |
| "Thalidomide (TD) displays remarkable species specificity, causing birth defects (teratogenesis) in humans and rabbits, but not rats or mice; yet, few determinants of species susceptibility have been identified." | 1.37 | Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture. ( Gonçalves, LL; Lee, CJ; Wells, PG, 2011) |
| "We have recently shown that Okihiro syndrome results from mutation in the putative zinc finger transcription factor gene SALL4 on chromosome 20q13." | 1.32 | Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy. ( Becker, K; Kohlhase, J; Liebers, M; Mohammed, SN; Newbury-Ecob, R; Rauch, A; Reardon, W; Schubert, L, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 74 (68.52) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (3.70) | 29.6817 |
| 2010's | 21 (19.44) | 24.3611 |
| 2020's | 9 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Niecke, A | 4 |
| Peters, KM | 4 |
| Alayli, A | 1 |
| Lüngen, M | 3 |
| Pfaff, H | 3 |
| Albus, C | 3 |
| Samel, C | 3 |
| Beyer, R | 3 |
| Schulte-Hillen, J | 1 |
| Stück, V | 1 |
| Rengel, BD | 1 |
| Kowalski, TW | 6 |
| Bremm, JM | 1 |
| do Amaral Gomes, J | 1 |
| Schüler-Faccini, L | 9 |
| Vianna, FSL | 3 |
| Fraga, LR | 6 |
| Passarge, E | 2 |
| Markiewicz, M | 1 |
| Stirling, P | 2 |
| Brennan, S | 1 |
| Hooper, G | 2 |
| Lam, W | 2 |
| Farr, S | 1 |
| Vargesson, N | 1 |
| Giddins, G | 1 |
| Hunter, A | 1 |
| Gomes, JDA | 1 |
| Garcia, GBC | 1 |
| Paixao-Cortes, VR | 1 |
| Recamonde-Mendoza, M | 1 |
| Sanseverino, MTV | 2 |
| Ramesh, I | 1 |
| Croci, DM | 1 |
| Dalolio, M | 1 |
| Schaeren, S | 1 |
| Wasner, MG | 1 |
| Mariani, L | 1 |
| Jost, GF | 1 |
| Weinrich, JM | 1 |
| Well, L | 1 |
| Tahir, E | 1 |
| Lindemann, M | 1 |
| Wilke, U | 1 |
| Adam, G | 1 |
| Bannas, P | 1 |
| Lund, GK | 1 |
| Yashiro, K | 1 |
| Miyagawa, S | 1 |
| Sawa, Y | 1 |
| Reimann, A | 1 |
| Mumm, R | 1 |
| Scheffler, C | 1 |
| Nippert, I | 1 |
| Hinoshita, F | 1 |
| Beppu, H | 1 |
| Shioji, S | 1 |
| Fujitani, J | 1 |
| Imai, K | 1 |
| Tajima, T | 1 |
| Tagami, T | 1 |
| Ohnishi, S | 1 |
| Leite, JCL | 1 |
| de Sousa, SHC | 1 |
| da Costa, LMM | 1 |
| Dias, MF | 1 |
| Morelo, EF | 1 |
| Doriqui, MJR | 1 |
| Maximino, CM | 2 |
| Parsa, CF | 1 |
| Robert, MP | 1 |
| Hoyt, CS | 1 |
| Vianna, FS | 5 |
| Tovo-Rodrigues, L | 3 |
| Tagliani-Ribeiro, A | 2 |
| Biondi, F | 1 |
| Sanseverino, MT | 6 |
| Hutz, MH | 3 |
| Shiga, T | 1 |
| Shimbo, T | 1 |
| Yoshizawa, A | 1 |
| Ghassemi Jahani, SA | 1 |
| Danielsson, A | 1 |
| Ab-Fawaz, R | 1 |
| Hebelka, H | 1 |
| Danielson, B | 1 |
| Brisby, H | 1 |
| Sales Luiz Vianna, F | 1 |
| Cassina, M | 1 |
| Cagnoli, GA | 1 |
| Zuccarello, D | 1 |
| Di Gianantonio, E | 1 |
| Clementi, M | 1 |
| Godoy, BA | 1 |
| Wells, PG | 3 |
| McCallum, GP | 1 |
| Lam, KC | 1 |
| Henderson, JT | 1 |
| Ondovcik, SL | 1 |
| Lee, CJ | 2 |
| Gonçalves, LL | 1 |
| Shibata, N | 1 |
| Wiley, MJ | 1 |
| Lopez-Camelo, JS | 1 |
| Leite, JC | 1 |
| Dutra, Mda G | 1 |
| Castilla, EE | 1 |
| Kohlhase, J | 1 |
| Schubert, L | 1 |
| Liebers, M | 1 |
| Rauch, A | 1 |
| Becker, K | 1 |
| Mohammed, SN | 1 |
| Newbury-Ecob, R | 1 |
| Reardon, W | 1 |
| BERGSTROM, AL | 1 |
| NILSSON, L | 1 |
| PETTERSSON, G | 1 |
| SODERLING, B | 1 |
| VICTORIN, L | 1 |
| WINBERG, J | 2 |
| BUKIET, V | 1 |
| MELLIN, GW | 2 |
| KATZENSTEIN, M | 2 |
| FARIZON, F | 1 |
| MASBERNARD, A | 1 |
| JOKI, T | 1 |
| VAANANEN, I | 1 |
| FORLEO, R | 1 |
| HIRSCH, M | 1 |
| SCHONENBERG, H | 1 |
| WEICKER, H | 6 |
| BACHMANN, KD | 3 |
| PFEIFFER, RA | 3 |
| GLEISS, J | 3 |
| HUNGERLAND, H | 1 |
| DAHLBERG, KH | 1 |
| HAGERSTRAND, I | 1 |
| KEMPER, F | 1 |
| KASS, E | 1 |
| SCHUMACHER, H | 1 |
| ODUNJO, F | 1 |
| MATTURRI, L | 2 |
| NODARI, R | 3 |
| ROBECCHI, E | 1 |
| KELSEY, FO | 3 |
| RAVAILLE, G | 1 |
| METZ, J | 1 |
| MAUER, ML | 1 |
| TORRICELLI, C | 1 |
| FELISATI, D | 1 |
| PARTSCH, CJ | 2 |
| MAURER, H | 1 |
| MAUSS, HJ | 1 |
| VOGL, A | 1 |
| VIVELL, O | 1 |
| COHLAN, SQ | 1 |
| LARSEN, V | 1 |
| ARENA, JM | 1 |
| INGALLS, TH | 1 |
| CURLEY, FJ | 1 |
| ZAPPASODI, P | 1 |
| ELSNER-MACKAY, P | 1 |
| KLEINSASSER, O | 1 |
| SCHLOTHANE, R | 1 |
| HEINE, W | 3 |
| KIRCHMAIR, H | 2 |
| FIEDLER, M | 2 |
| STUEWE, W | 2 |
| SCHMIDT, JG | 1 |
| TERRAHE, K | 1 |
| MAIER, WA | 1 |
| ERFURTH, F | 1 |
| MCCOLL, JD | 1 |
| GLOBUS, M | 1 |
| ROBINSON, S | 1 |
| DE JONGE, GA | 1 |
| KENEZ, J | 1 |
| LENZ, W | 5 |
| KNAPP, K | 2 |
| Paumgartten, FJ | 1 |
| Chahoud, I | 1 |
| Gleeson, K | 1 |
| Muto, R | 1 |
| Ohashi, H | 1 |
| Matthiass, HH | 1 |
| Ruffing, L | 1 |
| Poswillo, D | 1 |
| Petter, C | 1 |
| Gollop, TR | 1 |
| Eigier, A | 1 |
| Guidugli Neto, J | 1 |
| Kanno, O | 1 |
| McBride, WG | 1 |
| Hicks, LJ | 1 |
| Smith, JR | 1 |
| Martin, IR | 1 |
| Shaw, DG | 1 |
| Robinson, RO | 1 |
| Fratta, ID | 1 |
| Wilson, JG | 2 |
| Schumacher, HJ | 1 |
| Terapane, J | 1 |
| Jordan, RL | 1 |
| Jackson, R | 1 |
| Cerutti, R | 1 |
| Suzuki, M | 1 |
| Murai, N | 1 |
| Warburg, M | 1 |
| Aeppli, L | 1 |
| Charachon, D | 1 |
| Morgon, MA | 1 |
| Kida, M | 1 |
| Kaiser, G | 1 |
| Barrow, MV | 1 |
| Steffek, AJ | 1 |
| King, CT | 1 |
| Lévêque, B | 1 |
12 reviews available for thalidomide and Embryopathies
| Article | Year |
|---|---|
[National Competence Network Contergan - Ensuring medical care for people with thalidomide embryopathy].
Topics: Aging; Female; Fetal Diseases; Humans; Patient Care; Psychophysiologic Disorders; Thalidomide | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
Thalidomide upper limb embryopathy - pathogenesis, past and present management and future considerations.
Topics: Abnormalities, Multiple; Adult; Child; Female; Fetal Diseases; Humans; Thalidomide; Upper Extremity | 2023 |
Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings.
Topics: Brazil; Endemic Diseases; Erythema Nodosum; Female; Fetal Diseases; Humans; Hypnotics and Sedatives; | 2013 |
Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits.
Topics: Animals; Benzo(a)pyrene; DNA; DNA Damage; DNA Repair; Embryo, Mammalian; Female; Fetal Diseases; Gua | 2010 |
[THALIDOMIDE EMBRYOPATHY. SURVEY AND PATHOGENIC MECHANISM].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Data Collection; Ectromelia; Embryology; Fetal | 1963 |
FETAL AND NEONATAL HAZARDS FROM DRUGS ADMINISTERED DURING PREGNANCY.
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Anticoagulants; Antimetabolites; Antineoplastic | 1964 |
[EXOGENOUS MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Alcohols; Androgens; Anesthetics; Congenital A | 1964 |
[Fetal thalidomide syndrome].
Topics: Abnormalities, Drug-Induced; Female; Fetal Diseases; Humans; Hypnotics and Sedatives; Infant, Newbor | 2001 |
Present status of drugs as teratogens in man.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics; | 1973 |
[Fetal diseases caused by environmental polltuion].
Topics: Abnormalities, Drug-Induced; Air Pollution; Congenital Abnormalities; Environment; Environmental Pol | 1971 |
The heterogeneity of microphthalmia in the mentally retarded.
Topics: Abnormalities, Multiple; Abortifacient Agents; Adolescent; Adult; Brain Injuries; Child, Preschool; | 1971 |
96 other studies available for thalidomide and Embryopathies
| Article | Year |
|---|---|
Health-related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross-sectional survey.
Topics: Cross-Sectional Studies; Female; Fetal Diseases; Humans; Male; Pain; Quality of Life; Thalidomide | 2022 |
Genetic evaluation of HAND2 gene and its effects on thalidomide embryopathy.
Topics: Abnormalities, Multiple; Basic Helix-Loop-Helix Transcription Factors; Female; Fetal Diseases; Genet | 2022 |
Age-related changes in patients with upper limb thalidomide embryopathy in the United Kingdom.
Topics: Abnormalities, Multiple; Female; Fetal Diseases; Humans; Neuralgia; Quality of Life; Thalidomide; Up | 2023 |
Commentary on Markiewicz et al. Age-related changes in patients with upper limb thalidomide embryopathy in the United Kingdom.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Fetal Diseases; Humans; Thalidomide; U | 2023 |
CRL4-Cereblon complex in Thalidomide Embryopathy: a translational investigation.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Child; Embryo, Mammalian; Embryonic Develop | 2020 |
[Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors].
Topics: Chronic Pain; Fetal Diseases; Humans; Prevalence; Surveys and Questionnaires; Thalidomide | 2021 |
Thalidomide Embryopathy as Possible Cause of Anterior Sacral Meningocele: A Case Report.
Topics: Abnormalities, Multiple; Fetal Diseases; Humans; Magnetic Resonance Imaging; Male; Meningocele; Midd | 2017 |
Assessment of Congenital Vascular and Organ Anomalies in Subjects With Thalidomide Embryopathy Using Non-Contrast Magnetic Resonance Angiography.
Topics: Congenital Abnormalities; Creatinine; Female; Fetal Diseases; Gallbladder; Glomerular Filtration Rat | 2018 |
A Lesson From the Thalidomide Tragedy - The Past Is Never Dead. It's Not Even Past. William Faulkner, From "Requiem for a Nun".
Topics: Fetal Diseases; Humans; Magnetic Resonance Angiography; Nuns; Thalidomide | 2018 |
Reference tables with centiles of limb to body height ratios of healthy human adults for assessing potential thalidomide embryopathy.
Topics: Adult; Aged; Body Height; Child; Female; Fetal Diseases; Germany; Humans; Infant, Newborn; Male; Mid | 2019 |
Life situation of women impaired by Thalidomide embryopathy in North Rhine-Westphalia - a comparative analysis of a recent cross-sectional study with earlier data.
Topics: Abnormalities, Drug-Induced; Adult; Cross-Sectional Studies; Female; Fetal Diseases; Germany; Humans | 2019 |
A nationwide survey regarding the life situations of patients with thalidomide embryopathy in Japan, 2018: First report.
Topics: Family; Family Characteristics; Female; Fetal Diseases; Health; Humans; Income; Japan; Male; Marital | 2019 |
Thromboembolism and congenital malformations: from Duane syndrome to thalidomide embryopathy.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Duane Retraction Syndrome; Eye Abnormalities; Female; F | 2013 |
No, not more talk about Duane syndrome.
Topics: Abnormalities, Drug-Induced; Duane Retraction Syndrome; Eye Abnormalities; Female; Fetal Diseases; H | 2013 |
Polymorphisms in the endothelial nitric oxide synthase gene in thalidomide embryopathy.
Topics: Fetal Diseases; Gene Frequency; Humans; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleot | 2013 |
Multicenter investigation of lifestyle-related diseases and visceral disorders in thalidomide embryopathy at around 50 years of age.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Cross-Sectional Studies; Female; Fetal Disease | 2015 |
Thalidomide embryopathy: Follow-up of cases born between 1959 and 2010.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Brazil; Child, Preschool; F | 2015 |
New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors.
Topics: Adolescent; Adult; Brazil; Child; Female; Fetal Diseases; Gene Frequency; Genetic Predisposition to | 2016 |
Degenerative Changes in the Cervical Spine Are More Common in Middle-Aged Individuals with Thalidomide Embryopathy than in Healthy Controls.
Topics: Adult; Case-Control Studies; Cervical Vertebrae; Constriction, Pathologic; Demography; Female; Fetal | 2016 |
The impact of thalidomide use in birth defects in Brazil.
Topics: Abnormalities, Multiple; Brazil; Congenital Abnormalities; Fetal Diseases; Humans; Leprosy; Teratoge | 2017 |
Human teratogens and genetic phenocopies. Understanding pathogenesis through human genes mutation.
Topics: Abnormalities, Drug-Induced; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Fetal Diseas | 2017 |
Genomic and in silico analyses of CRBN gene and thalidomide embryopathy in humans.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adaptor Proteins, Signal Transducing; Binding | 2016 |
Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture.
Topics: Abnormalities, Drug-Induced; Animals; DNA Damage; DNA Glycosylases; DNA Repair; DNA Repair-Deficienc | 2011 |
Fluorothalidomide: a characterization of maternal and developmental toxicity in rabbits and mice.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationsh | 2011 |
Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil.
Topics: Abnormalities, Drug-Induced; Adult; Brazil; Female; Fetal Diseases; Geography; Humans; Infant, Newbo | 2011 |
Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy.
Topics: Abnormalities, Multiple; Base Sequence; Chromosomes, Human, Pair 20; DNA; DNA Mutational Analysis; D | 2003 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Syndrome | 1962 |
[Embryopathies caused by thalidomide].
Topics: Extremities; Fetal Diseases; Hypnotics and Sedatives; Limb Deformities, Congenital; Thalidomide | 1962 |
The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies.
Topics: Ectromelia; Fetal Diseases; Peripheral Nervous System Diseases; Thalidomide | 1962 |
The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies.
Topics: Congenital Abnormalities; Fetal Diseases; Humans; Neurology; Peripheral Nervous System Diseases; Tha | 1962 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Ectromelia; Fetal Diseases; Humans; Syndrome; Thalidomide | 1962 |
[Thalidomide and embryopathies. Report of 2 cases].
Topics: Congenital Abnormalities; Fetal Diseases; Thalidomide | 1962 |
[Responsibility of thalidomide in the etiology of some fetal malformations. On embryopathy caused by chemotherapy].
Topics: Ectromelia; Fetal Diseases; Humans; Social Behavior; Thalidomide | 1962 |
[Chromosomal studies on so-called thalidomide embryopathy].
Topics: Abnormalities, Multiple; Ectromelia; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
Thalidomide embryopathy.
Topics: Abnormalities, Multiple; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Ectromelia; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
[Thalidomide embryopathy. II. Results of individual anamnestic findings in the areas of inquiry of the universities of Bonn, Cologne, Muenster and Duesseldorf pediatric clinics].
Topics: Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Research; Syndrome; Thalidomide; | 1962 |
[Thalidomide embryopathy. I. Incidence inside and outside Germany].
Topics: Fetal Diseases; Germany; Hypnotics and Sedatives; Incidence; Syndrome; Thalidomide | 1962 |
[Extreme cases of fetal injury possibly induced by thalidomide].
Topics: Ectromelia; Fetal Diseases; Thalidomide | 1962 |
[Chick egg embryopathy].
Topics: Animals; Chickens; Congenital Abnormalities; Fetal Diseases; Thalidomide | 1963 |
[THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Multiple; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
[PERSISTENT TRUNCUS ARTERIOSUS COMMUNIS IN SO-CALLED THALIDOMIDE EMBRYOPATHY].
Topics: Ductus Arteriosus; Ectromelia; Fetal Diseases; Heart Septal Defects; Heart Septal Defects, Ventricul | 1963 |
[ANATOMOCLINICAL STUDY OF 19 CASES OF EMBRYOPATHY CAUSED BY THALIDOMIDE].
Topics: Appendix; Congenital Abnormalities; Ectromelia; Female; Fetal Diseases; Heart Defects, Congenital; H | 1963 |
[MEDICAL THERAPY IN PREGNANCY AND ITS REPERCUSSIONS ON THE FETUS].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgens; Anti-Bacterial Agents; Anticoagulan | 1963 |
DRUG EMBRYOPATHY: THE THALIDOMIDE STORY.
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Female; Fetal Diseases; Glutethimide; Humans; In | 1963 |
[1ST CASE OF THALIDOMIDE EMBRYOPATHY STUDIED IN FRANCE].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ectromelia; Fetal Diseases; France; Infant, Ne | 1963 |
[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. 3].
Topics: Abnormalities, Drug-Induced; Diseases in Twins; Ectromelia; Fetal Diseases; Infant, Newborn; Syndrom | 1963 |
PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY 1960-1961.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fetal Diseases; Geriatrics; Germany; Germany, | 1964 |
[THALIDOMIDE EMBRYOPATHY IN ITALY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fetal Diseases; Italy; Statistics as Topic; Sy | 1963 |
[THALIDOMIDE EMBRYOPATHIES IN MILANO AND SUBURBS. ANATOMO-CLINICAL STUDY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Biomedical Research; Ectromelia; Fetal Disease | 1963 |
[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. III].
Topics: Abnormalities, Drug-Induced; Diseases in Twins; Ectromelia; Fetal Diseases; Infant, Newborn; Syndrom | 1963 |
[TOXIC AND TERATOGENIC EFFECTS OF THALIDOMIDE ON A RABBIT FETUS].
Topics: Abnormalities, Drug-Induced; Animals, Newborn; Ectromelia; Fetal Diseases; Fetus; Pregnancy; Pregnan | 1963 |
[ON THE FORMAL GENESIS OF EAR ABNORMALITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Coenzymes; Ear; Fetal Diseases; Humans; Infant | 1963 |
[DRUG USE DURING PREGNANCY AFTER DISCOVERY OF THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Ectromelia; Female; | 1964 |
[TERATOGENIC SUBSTANCES?].
Topics: Abnormalities, Drug-Induced; Ectromelia; Fetal Diseases; Infant, Newborn; Meclizine; Phenmetrazine; | 1964 |
THE TERATOGENIC EFFECTS OF THALIDOMIDE, IMIPRAMINE HC1 AND IMIPRAMINE-N-OXIDE HC1 ON WHITE DANISH RABBITS.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Female; Fetal Diseases; Humans; Imipramine; | 1963 |
[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Congenital Abnormalities; Cryptorchidism; Ear Deformities | 1964 |
[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di | 1964 |
REPORT FROM THE DUKE UNIVERSITY POISON CONTROL CENTER. DRUG DANGERS (MATERNAL MEDICATION) TO THE FETUS.
Topics: Abnormalities, Drug-Induced; Aminopterin; Anti-Bacterial Agents; Antimetabolites; Chloramphenicol; C | 1964 |
THALIDOMIDE EMBRYOPATHY IN HYBRID RABBITS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Extremities; Female; Fetal Diseases; Humans; K | 1964 |
[EAR MALFORMATIONS IN THE FRAMEWORK OF THALIDOMIDE EMBRYOPATHY. (BASED ON A SURVEY OF 70 INFANTS BORN DURING 1959-1962)].
Topics: Abnormalities, Drug-Induced; Deafness; Ear Deformities, Acquired; Ear, External; Fetal Diseases; Hea | 1964 |
[THALIDOMIDE EMBRYOPATHY IN RABBITS FOLLOWING TRANSIENT LIVER DAMAGE IN THE MOTHER BY CARBON TETRACHLORIDE].
Topics: Abnormalities, Drug-Induced; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical | 1964 |
[OCULOMOTOR PARALYSIS IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Female; Fetal Diseases; Ophthalmoplegia | 1964 |
[ABNORMALITIES OF THE INTERNAL AND MIDDLE EAR AS A SEQUEL TO THALIDOMIDE EMBRYOPATHY--RESULTS OF TOMOGRAPHIC EXAMINATIONS OF THE EAR].
Topics: Abnormalities, Drug-Induced; Cochlear Nerve; Ear, Middle; Facial Nerve; Facial Paralysis; Fetal Dise | 1965 |
THALIDOMIDE EMBRYOPATHY AND LIMB DEFECTS; ESPERIENCES IN HABILITATION OF CHILDREN WITH ECTROMELIAS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Angiography; Artificial Limbs; Child; Ectromel | 1965 |
PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY, 1960-1961.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Drug Industry; Female; Fetal Diseases; Germany | 1965 |
[ROENTGENOLOGIC CHANGES IN RABBIT THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Carbon Tetrachloride; Ectromelia; Fet | 1965 |
AN ATTEMPTED REVERSAL OF THALIDOMIDE EMBRYOPATHY IN THE RAT BY GLUTAMINE.
Topics: Abnormalities, Drug-Induced; Fetal Diseases; Glutamates; Glutamine; Pathology; Pharmacology; Pregnan | 1965 |
[THALIDOMIDE EMBRYOPATHY IN ANIMAL EXPERIMENT. REPRODUCTION OF THE THALIDOMIDE EMBRYOPATHY IN A TERATOLOGIC EXPERIMENT IN RABBITS WITH TRANSIENT LIVER DAMAGE].
Topics: Abnormalities, Drug-Induced; Animal Experimentation; Animals; Carbon Tetrachloride Poisoning; Female | 1964 |
[SIMILARITIES AND PECULIARITIES OF FANCONI'S ANEMIA AND THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Multiple; Anemia; Anemia, Aplastic; Diagnosis, Differential; Ectromelia; Fanconi Anem | 1964 |
[FETAL DAMAGE CAUSED BY PHARMACEUTICAL AGENTS].
Topics: Abnormalities, Drug-Induced; Endocrine System Diseases; Fetal Diseases; Humans; Morphine Dependence; | 1965 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Extremities; Fetal Diseases; Hypnotics and Sedatives; Limb Deformities, Con | 1962 |
Thalidomide embryopathy.
Topics: Abnormalities, Multiple; Extremities; Fetal Diseases; Hypnotics and Sedatives; Limb Deformities, Con | 1962 |
[Thalidomide embryopathy].
Topics: Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Syndrome; Thalidomide | 1962 |
Thalidomide embryopathy cases in Brazil after 1965.
Topics: Adult; Brazil; Drug Utilization Review; Erythema Nodosum; Female; Fetal Diseases; Humans; Leprosy, L | 2006 |
Bracket creep in Australian abortion indications: when did rubella arrive?
Topics: Abortion, Induced; Australia; Fetal Diseases; Humans; New South Wales; Rubella; Thalidomide; United | 2007 |
[The development of the postural and motor apparatus in juveniles with thalidomide embryopathy].
Topics: Ectromelia; Female; Fetal Diseases; Hip Joint; Humans; Musculoskeletal Development; Pregnancy; Shoul | 1978 |
Hemorrhage in development of the face.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Arteries; Craniofacial Dysostosis; Di | 1975 |
Early foetal thrombosis induced by thalidomide in mouse: possible explanation for teratogenicity.
Topics: Animals; Extremities; Female; Fetal Diseases; Hemorrhage; Mice; Mice, Inbred C57BL; Pregnancy; Thali | 1977 |
Prenatal diagnosis of thalidomide syndrome.
Topics: Abnormalities, Drug-Induced; Adult; Ectromelia; Female; Fetal Diseases; Humans; Pregnancy; Prenatal | 1987 |
Electroencephalographic study of 137 patients with thalidomide embryopathy.
Topics: Adolescent; Adult; Brain; Child; Electroencephalography; Epilepsy; Female; Fetal Diseases; Hearing D | 1987 |
Acetylcholine and choline levels in rabbit fetuses exposed to anticholinergics.
Topics: Acetylcholine; Animals; Choline; Female; Fetal Diseases; Fetus; Gestational Age; Maternal-Fetal Exch | 1987 |
Progressive non-infectious anterior vertebral fusion.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Fetal Diseases; Humans; Kyphosis; Lumbar V | 1986 |
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma | 1969 |
The teratogenic activity of a thalidomide analogue, EM 12 in rabbits, rats, and monkeys.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Bone Diseases, Developmental; Female; Fetal De | 1972 |
The fetus: medicine's newest patient.
Topics: Abnormalities, Drug-Induced; Embryonic and Fetal Development; Female; Fetal Diseases; Fetus; Humans; | 1973 |
[Action of psychopharmacological agents on the product of conception].
Topics: Abnormalities, Drug-Induced; Amphetamine; Animals; Anticonvulsants; Embryo, Mammalian; Female; Fetal | 1973 |
[A comparison of the sensitive phase for thalidomide in animal experiment and in man].
Topics: Abnormalities, Drug-Induced; Animals; Arm; Ear; Female; Fetal Diseases; Haplorhini; Humans; Infant, | 1968 |
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc | 1969 |
Phenocopy.
Topics: Abnormalities, Multiple; Anemia, Aplastic; Arm; Congenital Hypothyroidism; Deafness; Female; Feminiz | 1970 |
[Lesions of the auditory apparatus during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Bacterial Infections; Deafness; Drug-Related Side Effects and | 1970 |
[Significance of exogenous influences for the development of human abnormalities].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Fetal Diseases; Humans; Infa | 1967 |
[Thalidomide embryopathy in Japan].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ear; Ectromelia; Female; Fetal Diseases; Finge | 1968 |
[Malformations].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Embryology; Female; Fetal Diseases; | 1968 |
Thalidomide syndrome in rhesus monkeys (Macaca mulatta).
Topics: Animals; Female; Fetal Diseases; Monkey Diseases; Pregnancy; Thalidomide | 1969 |
[Embryopathies and fetal diseases of therapeutic origin].
Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Anticoagulants; Antimalarials; Antineop | 1966 |