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thalidomide and Disseminated Intravascular Coagulation

thalidomide has been researched along with Disseminated Intravascular Coagulation in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide 100 mg/day stabilized multiple angiomatosis better than interferon alfa."7.78[Chronic disseminated intravascular coagulation (DIC) markers in a patient with multiple angiomatosis during treatment with anti-angiogenics: interferon α, thalidomide and lenalidomide]. ( Adam, Z; Hájek, R; Koukalová, R; Král, Z; Krejčí, M; Křikavová, L; Matýšková, M; Mayer, J; Navrátil, M; Nebeský, T; Neuman, C; Pour, L; Rehák, Z; Szturz, P; Tomíška, M, 2012)
"Thalidomide 100 mg/day stabilized multiple angiomatosis better than interferon alfa."3.78[Chronic disseminated intravascular coagulation (DIC) markers in a patient with multiple angiomatosis during treatment with anti-angiogenics: interferon α, thalidomide and lenalidomide]. ( Adam, Z; Hájek, R; Koukalová, R; Král, Z; Krejčí, M; Křikavová, L; Matýšková, M; Mayer, J; Navrátil, M; Nebeský, T; Neuman, C; Pour, L; Rehák, Z; Szturz, P; Tomíška, M, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asakura, H1
Adam, Z1
Pour, L1
Matýšková, M1
Krejčí, M1
Tomíška, M1
Szturz, P1
Rehák, Z1
Koukalová, R1
Křikavová, L1
Nebeský, T1
Neuman, C1
Navrátil, M1
Hájek, R1
Král, Z1
Mayer, J1

Reviews

1 review available for thalidomide and Disseminated Intravascular Coagulation

ArticleYear
[Thrombosis and DIC in hematological malignancies].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Annexin A2; Antineoplastic Agents; Asparaginase; Cytokines; Disseminated Intravascular Coagulation;

2014

Other Studies

1 other study available for thalidomide and Disseminated Intravascular Coagulation

ArticleYear
[Chronic disseminated intravascular coagulation (DIC) markers in a patient with multiple angiomatosis during treatment with anti-angiogenics: interferon α, thalidomide and lenalidomide].
    Vnitrni lekarstvi, 2012, Volume: 58, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Angiomatosis; Biomarkers; Disseminated Intravascular Coagulation; Hu

2012