thalidomide has been researched along with Diabetic Retinopathy in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to compare the therapeutic effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats." | 7.72 | Effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats. ( Bosco, AA; Lerario, AC; Santos, RF; Wajchenberg, BL, 2003) |
| "Diabetic retinopathy is an ocular complication associated with the chronic endocrine disorder of diabetes mellitus." | 6.55 | Significance of the antiangiogenic mechanisms of thalidomide in the therapy of diabetic retinopathy. ( Behl, T; Goel, H; Kaur, I; Kotwani, A, 2017) |
| "Our aim was to compare the therapeutic effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats." | 3.72 | Effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats. ( Bosco, AA; Lerario, AC; Santos, RF; Wajchenberg, BL, 2003) |
| "Diabetic retinopathy is an ocular complication associated with the chronic endocrine disorder of diabetes mellitus." | 2.55 | Significance of the antiangiogenic mechanisms of thalidomide in the therapy of diabetic retinopathy. ( Behl, T; Goel, H; Kaur, I; Kotwani, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, K | 1 |
| Murthy, H | 1 |
| Muralidhar, NS | 1 |
| Rani, PK | 1 |
| Behl, T | 1 |
| Kaur, I | 1 |
| Goel, H | 1 |
| Kotwani, A | 1 |
| Dong, LF | 1 |
| Yao, J | 1 |
| Wang, XQ | 1 |
| Shan, K | 1 |
| Yang, H | 1 |
| Yan, B | 1 |
| Jiang, Q | 1 |
| Bosco, AA | 1 |
| Lerario, AC | 1 |
| Santos, RF | 1 |
| Wajchenberg, BL | 1 |
| Kumar, S | 1 |
| Li, C | 1 |
1 review available for thalidomide and Diabetic Retinopathy
| Article | Year |
|---|---|
Significance of the antiangiogenic mechanisms of thalidomide in the therapy of diabetic retinopathy.
Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Diabetic Retinopathy; Humans; Neovascularizat | 2017 |
5 other studies available for thalidomide and Diabetic Retinopathy
| Article | Year |
|---|---|
Multiple myeloma masquerading as diabetic macular oedema.
Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Large-Core Needle; Bone Marrow; Cycl | 2018 |
Lenalidomide, an anti-tumor drug, regulates retinal endothelial cell function: Implication for treating ocular neovascular disorder.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line; Cell Movement; Cell Survival; Ch | 2015 |
Effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats.
Topics: Angiogenesis Inhibitors; Animals; Aqueous Humor; Capillaries; Diabetes Mellitus, Experimental; Diabe | 2003 |
Rethinking thalidomide.
Topics: Animals; Diabetic Retinopathy; Eye; Humans; Macular Degeneration; Neovascularization, Pathologic; Ra | 1995 |
Targeting of vasculature in cancer and other angiogenic diseases.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antigens, CD; Arthritis, Rheumatoid; Diabetic Retin | 2001 |