thalidomide has been researched along with Diabetic Glomerulosclerosis in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with thalidomide markedly stimulated the phosphorylation of AMPKα." | 1.48 | Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway. ( Li, R; Wang, B; Wang, Y; Yang, Y; Zhang, H, 2018) |
| "Thermal hyperalgesia and mechanical allodynia were measured using planter test and dynamic aesthesiometer (Ugo-Basile, Italy), respectively." | 1.38 | Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats. ( Sharma, PL; Taliyan, R, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, HX | 1 |
| Yuan, J | 1 |
| Li, RS | 1 |
| Zhang, H | 1 |
| Yang, Y | 1 |
| Wang, Y | 1 |
| Wang, B | 1 |
| Li, R | 1 |
| Ninan, MJ | 1 |
| Datta, YH | 1 |
| Alexander, MP | 1 |
| Nasr, SH | 1 |
| Watson, DC | 1 |
| Méndez, GP | 1 |
| Rennke, HG | 1 |
| Taliyan, R | 1 |
| Sharma, PL | 1 |
2 reviews available for thalidomide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Post-transplant lymphoproliferative disorder presenting as multiple myeloma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2010 |
Renal crescentic alpha heavy chain deposition disease: a report of 3 cases and review of the literature.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cuti | 2011 |
3 other studies available for thalidomide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Thalidomide Mitigates Apoptosis via Endoplasmic Reticulum Stress in Diabetic Nephropathy.
Topics: Animals; Apoptosis; Caspase 12; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic | 2022 |
Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cytokines; Cytoprotection; Diabete | 2018 |
Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; Diabe | 2012 |