thalidomide has been researched along with Di Guglielmo Disease in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has been reported to have anti-AML activity and appears to cross the blood brain barrier (BBB)." | 1.32 | Thalidomide is highly effective in a patient with meningeal acute myeloid leukaemia. ( Baird, R; Duddy, J; Iveson, A; Rassam, SM; van Zyl-Smit, RN, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thakral, B | 1 |
| Wang, SA | 1 |
| Baird, R | 1 |
| van Zyl-Smit, RN | 1 |
| Iveson, A | 1 |
| Duddy, J | 1 |
| Rassam, SM | 1 |
| Louzir, B | 1 |
| Othmani, S | 1 |
| Gritli, N | 1 |
| Beji, M | 1 |
| Zidi, B | 1 |
| M'Saddek, F | 1 |
| Boussema, E | 1 |
| Bahri, M | 1 |
3 other studies available for thalidomide and Di Guglielmo Disease
| Article | Year |
|---|---|
"Hof" in pronormoblasts: pure erythroid leukemia mimicking plasma cell myeloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cyclophosphamide; Cytoplasm; Dexa | 2017 |
Thalidomide is highly effective in a patient with meningeal acute myeloid leukaemia.
Topics: Adult; Fatal Outcome; Female; Humans; Leukemia, Erythroblastic, Acute; Lymphoma, B-Cell; Meningeal N | 2004 |
[Erythroleukemia in a patient with Behçet's disease under long-term thalidomide therapy].
Topics: Adult; Behcet Syndrome; Humans; Leukemia, Erythroblastic, Acute; Male; Thalidomide; Time Factors | 1992 |