Page last updated: 2024-11-05

thalidomide and Dermatitis, Exfoliative

thalidomide has been researched along with Dermatitis, Exfoliative in 8 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Dermatitis, Exfoliative: The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We report a case of toxic pustuloderma secondary to thalidomide in a patient with severe nodular prurigo."3.69Thalidomide-induced toxic pustuloderma. ( Basarab, T; Darvay, A; Russell-Jones, R, 1997)
"In cases of malignancy that are refractive to treatment, other therapies have been found to be effective for paraneoplastic itch, including selective serotonin reuptake inhibitors, mirtazapine, gabapentin, thalidomide, opioids, aprepitant, and histone deacetylase inhibitors."2.53Paraneoplastic Itch Management. ( Rowe, B; Yosipovitch, G, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Yin, X1
Huang, C1
Feng, Y1
Xia, J1
Zhang, M1
Yin, Z1
Chen, X1
Wang, S1
Mugheddu, C1
Pizzatti, L1
Sanna, S1
Atzori, L1
Rongioletti, F1
Krishnamoorthy, G1
Kotecha, A1
Pimentel, J1
Rowe, B1
Yosipovitch, G1
Rose, AE1
Patel, U1
Chu, J1
Patel, R1
Meehan, S1
Latkowski, JA1
Bielsa, I1
Teixidó, J1
Ribera, M1
Ferrándiz, C1
Darvay, A1
Basarab, T1
Russell-Jones, R1

Reviews

2 reviews available for thalidomide and Dermatitis, Exfoliative

ArticleYear
Paraneoplastic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Acantholysis; Acanthosis Nigricans; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Apre

2016
Erythrodermic lichen planus.
    Dermatology online journal, 2011, Oct-15, Volume: 17, Issue:10

    Topics: Aged; Chills; Dermatitis, Exfoliative; Glucocorticoids; Humans; Immunologic Factors; Itraconazole; L

2011

Other Studies

6 other studies available for thalidomide and Dermatitis, Exfoliative

ArticleYear
Apremilast for the treatment of papuloerythroderma of Ofuji.
    Clinical and experimental dermatology, 2023, 10-25, Volume: 48, Issue:11

    Topics: Dermatitis, Exfoliative; Humans; Skin Diseases, Papulosquamous; Thalidomide

2023
Case of erythrodermic lichen planus successful treated with thalidomide monotherapy.
    The Journal of dermatology, 2020, Volume: 47, Issue:6

    Topics: Administration, Oral; Dermatitis, Exfoliative; Humans; Lichen Planus; Male; Middle Aged; Skin; Thali

2020
COVID-19 pulmonary infection in erythrodermic psoriatic patient with oligodendroglioma: safety and compatibility of apremilast with critical intensive care management.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2020, Volume: 34, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Betacoronavirus; Coronavirus Infections; COVID-19; Critical

2020
Complete resolution of erythrodermic psoriasis with first-line apremilast monotherapy.
    BMJ case reports, 2019, Jan-31, Volume: 12, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Exfoliative; Humans; Male; Middle Aged; Pruritu

2019
Erythroderma due to thalidomide: report of two cases.
    Dermatology (Basel, Switzerland), 1994, Volume: 189, Issue:2

    Topics: Adult; Dermatitis, Exfoliative; Drug Eruptions; Eosinophilia; Female; Humans; Kidney Failure, Chroni

1994
Thalidomide-induced toxic pustuloderma.
    Clinical and experimental dermatology, 1997, Volume: 22, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Exfoliative; Drug Eruptions; Female; Hum

1997