thalidomide has been researched along with Dental Caries in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Dental Caries: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Crohn's disease is a chronic inflammatory disease, which may involve any part of the gastrointestinal tract, including the oral cavity." | 2.41 | [Oral aspects of Crohn's disease]. ( Brand, HS; Scheper, HJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekfeldt, A | 1 |
| Carlsson, GE | 1 |
| Scheper, HJ | 1 |
| Brand, HS | 1 |
| Stahl, A | 1 |
1 review available for thalidomide and Dental Caries
| Article | Year |
|---|---|
[Oral aspects of Crohn's disease].
Topics: Crohn Disease; Dental Caries; Genetic Predisposition to Disease; Humans; Immunosuppressive Agents; O | 2000 |
2 other studies available for thalidomide and Dental Caries
| Article | Year |
|---|---|
Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study.
Topics: Abnormalities, Drug-Induced; Anodontia; Dental Care for Disabled; Dental Caries; DMF Index; Female; | 2008 |
[Dysplasia in the mouth, jaw and teeth in dysmelia. Contribution to the thalidomide-embryopathies].
Topics: Abnormalities, Drug-Induced; Dental Caries; Ectromelia; Female; Humans; Infant, Newborn; Male; Pregn | 1967 |