thalidomide has been researched along with Demyelinating Diseases in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Larsen, LH | 1 |
| Lund, T | 1 |
| Vilholm, OJ | 1 |
| Plesner, T | 1 |
| Kuwabara, S | 1 |
| Thomas, PK | 1 |
2 reviews available for thalidomide and Demyelinating Diseases
| Article | Year |
|---|---|
[New treatment strategy for Crow-Fukase (POEMS) syndrome].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Boronic Acids; Bortezomib; | 2010 |
The morphological basis for alterations in nerve conduction in peripheral neuropathy.
Topics: Amyloidosis; Animals; Axons; Beriberi; Cresols; Demyelinating Diseases; Diabetic Neuropathies; Diffu | 1971 |
1 other study available for thalidomide and Demyelinating Diseases
| Article | Year |
|---|---|
Anti-myelin associated glycoprotein neuropathy responding to lenalidomide.
Topics: Aged; Antineoplastic Agents; Demyelinating Diseases; Humans; Immunoglobulin M; Lenalidomide; Male; M | 2011 |