Page last updated: 2024-11-05

thalidomide and Deafness

thalidomide has been researched along with Deafness in 21 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Research Excerpts

ExcerptRelevanceReference
"Of a population of 100 Swedish thalidomide embryopathy cases, at least four met full criteria for DSM-III-R autistic disorder and ICD-10 childhood autism."7.69Autism in thalidomide embryopathy: a population study. ( Akerström, B; Gillberg, C; Miller, M; Nordin, V; Strömland, K, 1994)
"Of a population of 100 Swedish thalidomide embryopathy cases, at least four met full criteria for DSM-III-R autistic disorder and ICD-10 childhood autism."3.69Autism in thalidomide embryopathy: a population study. ( Akerström, B; Gillberg, C; Miller, M; Nordin, V; Strömland, K, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199019 (90.48)18.7374
1990's1 (4.76)18.2507
2000's0 (0.00)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D AVIGNON, M1
BARR, B1
KLEINSASSER, O1
SCHLOTHANE, R1
Hörbst, L1
Strömland, K1
Nordin, V1
Miller, M1
Akerström, B1
Gillberg, C1
Takemori, S1
Tanaka, Y1
Suzuki, JI1
François, J1
Jörgensen, G3
Morgon, A1
Charachon, D2
Bringuier, N1
Paulsen, K1
Depaepe, E1
Terrahe, K1
Potter, GD1
Partsch, CJ1
Lenz, W1
Swingle, JD1
Bennett, M1
Morgon, MA1
Maran, AG1
Mongeau, M1
Gingras, G1
Sherman, ED1
Hebert, B1
Hutchison, J1
Corriveau, C1

Reviews

2 reviews available for thalidomide and Deafness

ArticleYear
Embryological pigment epithelial dystrophies.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1976, Volume: 172, Issue:6

    Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Deafness; Female; Fluorescein Angiography; Human

1976
[Human genetic aspects of inborn ear, nose, and throat diseases].
    HNO, 1985, Volume: 33, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Child, Preschool; Chro

1985

Other Studies

19 other studies available for thalidomide and Deafness

ArticleYear
Thalidomide: deafness.
    Prescrire international, 2012, Volume: 21, Issue:124

    Topics: Deafness; Humans; Thalidomide

2012
EAR ABNORMALITIES AND CRANIAL NERVE PALSIES IN THALIDOMIDE CHILDREN.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80

    Topics: Abnormalities, Drug-Induced; Child; Cranial Nerve Diseases; Cranial Nerves; Deafness; Ear Deformitie

1964
[EAR MALFORMATIONS IN THE FRAMEWORK OF THALIDOMIDE EMBRYOPATHY. (BASED ON A SURVEY OF 70 INFANTS BORN DURING 1959-1962)].
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1964, Volume: 43

    Topics: Abnormalities, Drug-Induced; Deafness; Ear Deformities, Acquired; Ear, External; Fetal Diseases; Hea

1964
[Surgical improvement of hearing in atresia auris congenita].
    Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1966, Volume: 100, Issue:4

    Topics: Abnormalities, Drug-Induced; Audiometry, Pure-Tone; Deafness; Ear, External; Female; Humans; Infant;

1966
Autism in thalidomide embryopathy: a population study.
    Developmental medicine and child neurology, 1994, Volume: 36, Issue:4

    Topics: Adult; Autistic Disorder; Deafness; Female; Humans; Intellectual Disability; Male; Pregnancy; Prenat

1994
Thalidomide anomalies of the ear.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1976, Volume: 102, Issue:7

    Topics: Abducens Nerve; Abnormalities, Drug-Induced; Adolescent; Child; Deafness; Ear; Ear, External; Ear, I

1976
[Abnormalities in the field of otorhinolaryngology. Genetic report].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Chromosome Aberrations

1972
[Malformations in otorhinolaryngology. Genetic report].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Chromosome Aberrations; Chromosome Diso

1972
Disorders of the auditory apparatus caused by embryopathy or foetopathy: prophylaxis and treatment (a) deafness as a result of congenital malformations occurring during the first three months (b) deafness resulting from diseases of the foetus occurring af
    Acta oto-laryngologica. Supplementum, 1971, Volume: 291

    Topics: Child, Preschool; Deafness; Ear; Ear, Inner; Female; Humans; Pregnancy; Pregnancy Complications; Rad

1971
Otological features in exomphalos-macro-glossia-gigantism syndrome (Wiedemann's syndrome).
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1973, Volume: 52, Issue:11

    Topics: Abnormalities, Drug-Induced; Adolescent; Audiometry; Deafness; Female; Gigantism; Hernia, Umbilical;

1973
[Surgical exploration of deafness due to thalidomide].
    Acta oto-rhino-laryngologica Belgica, 1974, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Child; Deafness; Ear; Ear, Inner;

1974
[Diagnosis of malformations of the ear and temporal bone].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:1

    Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos

1972
Michel's deafness.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1972, Volume: 96, Issue:3

    Topics: Abnormalities, Drug-Induced; Child; Deafness; Ear Canal; Ear, Inner; Female; Humans; Pregnancy; Thal

1972
[Congenital ear abnormalities as a cause of deafness].
    Annales Universitatis Saraviensis. Medizin, 1969, Volume: 16, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Anura; Cats; Chick Embryo; Congenital Abnormalities; Cricetina

1969
Phenocopy.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Abnormalities, Multiple; Anemia, Aplastic; Arm; Congenital Hypothyroidism; Deafness; Female; Feminiz

1970
Roentgenographic changes in healed meningococcal labyrinthitis.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1970, Volume: 92, Issue:3

    Topics: Abnormalities, Drug-Induced; Child; Deafness; Diagnosis, Differential; Ear, Inner; Humans; Labyrinth

1970
[Lesions of the auditory apparatus during pregnancy].
    Journal de medecine de Lyon, 1970, Nov-20, Volume: 51, Issue:197

    Topics: Abnormalities, Drug-Induced; Animals; Bacterial Infections; Deafness; Drug-Related Side Effects and

1970
Persistent stapedial artery.
    The Journal of laryngology and otology, 1965, Volume: 79, Issue:11

    Topics: Abnormalities, Drug-Induced; Child, Preschool; Deafness; Ear Ossicles; Ear, Middle; Female; Humans;

1965
Medical and psychosocial aspects of the habilitation of thalidomide children.
    Canadian Medical Association journal, 1966, Aug-27, Volume: 95, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Artificial Limbs; Child, Preschool; Deafness; Ear Deformities, A

1966