thalidomide has been researched along with Cytomegalovirus Infections in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Cytomegalovirus Infections: Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Groves, IJ | 1 |
| Jackson, SE | 1 |
| Poole, EL | 1 |
| Nachshon, A | 1 |
| Rozman, B | 1 |
| Schwartz, M | 1 |
| Prinjha, RK | 1 |
| Tough, DF | 1 |
| Sinclair, JH | 1 |
| Wills, MR | 1 |
| Kim, JH | 1 |
| Goulston, C | 1 |
| Sanders, S | 1 |
| Lampas, M | 1 |
| Zangari, M | 1 |
| Tricot, G | 1 |
| Hanson, KE | 1 |
| Haslett, PA | 1 |
| Hanekom, WA | 1 |
| Muller, G | 1 |
| Kaplan, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacologic T Cell Costimulation In HIV Disease[NCT00053430] | Phase 2 | 40 participants (Actual) | Interventional | 2001-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for thalidomide and Cytomegalovirus Infections
| Article | Year |
|---|---|
Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention.
Topics: Azepines; Bacterial Proteins; Benzodiazepines; Cell Cycle Proteins; Cyclin T; Cyclin-Dependent Kinas | 2021 |
Cytomegalovirus reactivation following autologous peripheral blood stem cell transplantation for multiple myeloma in the era of novel chemotherapeutics and tandem transplantation.
Topics: Aged; Antiviral Agents; Boronic Acids; Bortezomib; Cytomegalovirus; Cytomegalovirus Infections; Fema | 2012 |
Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro.
Topics: Adjuvants, Immunologic; CD8-Positive T-Lymphocytes; Cell Division; Coculture Techniques; Cytokines; | 2003 |