Page last updated: 2024-11-05

thalidomide and Craniofacial Dysarthrosis

thalidomide has been researched along with Craniofacial Dysarthrosis in 6 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
" Animal models of hemifacial microsomia and thalidomide-induced otomandibular dysostosis are described; the causal mechanism of malformation appeared to be closely related to the formation of a hematoma at the time of development of the stapedial arterial systems."3.65Hemorrhage in development of the face. ( Poswillo, D, 1975)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KITTEL, G1
Beckmann, G1
Jacobsson, C1
Granström, G1
Poswillo, D1
Miehlke, A1
Terrahe, K1

Reviews

1 review available for thalidomide and Craniofacial Dysarthrosis

ArticleYear
[Combined abnormalities of the ear and eye].
    HNO, 1967, Volume: 15, Issue:4

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Craniofacial Dysostosis; Ear; Embryology; Eye

1967

Other Studies

5 other studies available for thalidomide and Craniofacial Dysarthrosis

ArticleYear
[Abnormalities of the visceral arch with reference to the developmental history and influences of Contergan].
    Archiv fur Ohren-, Nasen- und Kehlkopfheilkunde, 1963, Volume: 181

    Topics: Branchial Region; Congenital Abnormalities; Craniofacial Dysostosis; Humans; Thalidomide

1963
[On form and extent of hearing loss in ear deformities partially caused by thalidomide].
    HNO, 1967, Volume: 15, Issue:2

    Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Craniofacial Dysostosis; Ear Deformities, Acqu

1967
Clinical appearance of spontaneous and induced first and second branchial arch syndromes.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 1997, Volume: 31, Issue:2

    Topics: Adult; Animals; Branchial Region; Craniofacial Dysostosis; Disease Models, Animal; Facial Asymmetry;

1997
Hemorrhage in development of the face.
    Birth defects original article series, 1975, Volume: 11, Issue:7

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Arteries; Craniofacial Dysostosis; Di

1975
[Diagnosis of malformations of the ear and temporal bone].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:1

    Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos

1972