thalidomide has been researched along with Craniofacial Dysarthrosis in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Animal models of hemifacial microsomia and thalidomide-induced otomandibular dysostosis are described; the causal mechanism of malformation appeared to be closely related to the formation of a hematoma at the time of development of the stapedial arterial systems." | 3.65 | Hemorrhage in development of the face. ( Poswillo, D, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KITTEL, G | 1 |
| Beckmann, G | 1 |
| Jacobsson, C | 1 |
| Granström, G | 1 |
| Poswillo, D | 1 |
| Miehlke, A | 1 |
| Terrahe, K | 1 |
1 review available for thalidomide and Craniofacial Dysarthrosis
| Article | Year |
|---|---|
[Combined abnormalities of the ear and eye].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Craniofacial Dysostosis; Ear; Embryology; Eye | 1967 |
5 other studies available for thalidomide and Craniofacial Dysarthrosis
| Article | Year |
|---|---|
[Abnormalities of the visceral arch with reference to the developmental history and influences of Contergan].
Topics: Branchial Region; Congenital Abnormalities; Craniofacial Dysostosis; Humans; Thalidomide | 1963 |
[On form and extent of hearing loss in ear deformities partially caused by thalidomide].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Craniofacial Dysostosis; Ear Deformities, Acqu | 1967 |
Clinical appearance of spontaneous and induced first and second branchial arch syndromes.
Topics: Adult; Animals; Branchial Region; Craniofacial Dysostosis; Disease Models, Animal; Facial Asymmetry; | 1997 |
Hemorrhage in development of the face.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Arteries; Craniofacial Dysostosis; Di | 1975 |
[Diagnosis of malformations of the ear and temporal bone].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos | 1972 |