thalidomide has been researched along with Coronary Disease in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The GENetic DEterminants of Restenosis (GENDER) project included 3104 patients who underwent a successful PCI." | 1.33 | Tumor necrosis factor-alpha plays an important role in restenosis development. ( 't Hart, LM; Agema, WR; Boesten, LS; de Maat, MP; de Vries, MR; de Winter, RJ; Doevendans, PA; Frants, RR; Havekes, LM; Jukema, JW; Monraats, PS; Pires, NM; Quax, PH; Schepers, A; Tio, RA; van der Laarse, A; van der Wall, EE; van Vlijmen, BJ; Waltenberger, J; Zwinderman, AH, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monraats, PS | 1 |
| Pires, NM | 1 |
| Schepers, A | 1 |
| Agema, WR | 1 |
| Boesten, LS | 1 |
| de Vries, MR | 1 |
| Zwinderman, AH | 1 |
| de Maat, MP | 1 |
| Doevendans, PA | 1 |
| de Winter, RJ | 1 |
| Tio, RA | 1 |
| Waltenberger, J | 1 |
| 't Hart, LM | 1 |
| Frants, RR | 1 |
| Quax, PH | 1 |
| van Vlijmen, BJ | 1 |
| Havekes, LM | 1 |
| van der Laarse, A | 1 |
| van der Wall, EE | 1 |
| Jukema, JW | 1 |
1 other study available for thalidomide and Coronary Disease
| Article | Year |
|---|---|
Tumor necrosis factor-alpha plays an important role in restenosis development.
Topics: Aged; Alleles; Angina Pectoris; Angiography; Angioplasty, Balloon, Coronary; Animals; Constriction, | 2005 |