thalidomide has been researched along with Corneal Injuries in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Corneal Injuries: Damage or trauma inflicted to the CORNEA by external means.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide is an effective inhibitor of corneal angiogenesis and prolongs graft survival as measured by graft clarity in donor corneas in eyes with previous neovascularization secondary to alkali injury." | 7.71 | Thalidomide prevents donor corneal graft neovascularization in an alkali burn model of corneal angiogenesis. ( Abbas, A; Feroze, AH; Hyman, GF; Khan, B, 2002) |
| "Thalidomide is an effective inhibitor of corneal angiogenesis and prolongs graft survival as measured by graft clarity in donor corneas in eyes with previous neovascularization secondary to alkali injury." | 3.71 | Thalidomide prevents donor corneal graft neovascularization in an alkali burn model of corneal angiogenesis. ( Abbas, A; Feroze, AH; Hyman, GF; Khan, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbas, A | 1 |
| Khan, B | 1 |
| Feroze, AH | 1 |
| Hyman, GF | 1 |
1 other study available for thalidomide and Corneal Injuries
| Article | Year |
|---|---|
Thalidomide prevents donor corneal graft neovascularization in an alkali burn model of corneal angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Burns, Chemical; Cornea; Corneal Injuries; Corneal Neovascularizat | 2002 |