Page last updated: 2024-11-05

thalidomide and Congenital Stiff-Man Syndrome

thalidomide has been researched along with Congenital Stiff-Man Syndrome in 1 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
" We report the first case of stiff-limb syndrome in a patient with multiple myeloma undergoing treatment with thalidomide, and explore the potential link to the cancer and its treatment."3.72Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma. ( Dalmau, J; Myers, DJ; Schiff, D, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schiff, D1
Dalmau, J1
Myers, DJ1

Other Studies

1 other study available for thalidomide and Congenital Stiff-Man Syndrome

ArticleYear
Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma.
    Journal of neuro-oncology, 2003, Volume: 65, Issue:2

    Topics: Female; Glutamate Decarboxylase; Humans; Immunoglobulin G; Middle Aged; Multiple Myeloma; Stiff-Pers

2003