thalidomide has been researched along with Congenital Stiff-Man Syndrome in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report the first case of stiff-limb syndrome in a patient with multiple myeloma undergoing treatment with thalidomide, and explore the potential link to the cancer and its treatment." | 3.72 | Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma. ( Dalmau, J; Myers, DJ; Schiff, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schiff, D | 1 |
| Dalmau, J | 1 |
| Myers, DJ | 1 |
1 other study available for thalidomide and Congenital Stiff-Man Syndrome
| Article | Year |
|---|---|
Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma.
Topics: Female; Glutamate Decarboxylase; Humans; Immunoglobulin G; Middle Aged; Multiple Myeloma; Stiff-Pers | 2003 |