Page last updated: 2024-11-05

thalidomide and Congenital Rubella Syndrome

thalidomide has been researched along with Congenital Rubella Syndrome in 4 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Environmental causes of birth defects have increasingly been recognized since the mid-20th century."2.47Causes of birth defects: lessons from history. ( Lancaster, PA, 2011)
"To evaluate the patterns of birth defects associated with diabetic embryopathy, a sensitivity-specificity analysis was performed on 4929 infants with major defects ascertained by the population-based Metropolitan Atlanta Congenital Defects Program between 1968 and 1980."1.28Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy. ( Becerra, JE; Cordero, JF; Erickson, JD; Khoury, MJ, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lancaster, PA1
Brent, R1
Fraser, C1
Khoury, MJ1
Becerra, JE1
Cordero, JF1
Erickson, JD1

Reviews

1 review available for thalidomide and Congenital Rubella Syndrome

ArticleYear
Causes of birth defects: lessons from history.
    Congenital anomalies, 2011, Volume: 51, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Australia; Congenital Abnormalities; Female; Fever; History, 2

2011

Other Studies

3 other studies available for thalidomide and Congenital Rubella Syndrome

ArticleYear
Correspondence.
    Birth defects research. Part A, Clinical and molecular teratology, 2012, Volume: 94, Issue:9

    Topics: Adenocarcinoma; Adolescent; Adult; Diethylstilbestrol; Female; Humans; Incidental Findings; Limb Def

2012
Regarding how safe is "safe"?
    Birth defects research. Part A, Clinical and molecular teratology, 2013, Volume: 97, Issue:1

    Topics: Adenocarcinoma; Diethylstilbestrol; Female; Humans; Limb Deformities, Congenital; Pregnancy; Rubella

2013
Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy.
    Pediatrics, 1989, Volume: 84, Issue:4

    Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Diabetes Mellitus, Type 1; Female; Georgia; H

1989