thalidomide has been researched along with Congenital Rubella Syndrome in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Environmental causes of birth defects have increasingly been recognized since the mid-20th century." | 2.47 | Causes of birth defects: lessons from history. ( Lancaster, PA, 2011) |
| "To evaluate the patterns of birth defects associated with diabetic embryopathy, a sensitivity-specificity analysis was performed on 4929 infants with major defects ascertained by the population-based Metropolitan Atlanta Congenital Defects Program between 1968 and 1980." | 1.28 | Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy. ( Becerra, JE; Cordero, JF; Erickson, JD; Khoury, MJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lancaster, PA | 1 |
| Brent, R | 1 |
| Fraser, C | 1 |
| Khoury, MJ | 1 |
| Becerra, JE | 1 |
| Cordero, JF | 1 |
| Erickson, JD | 1 |
1 review available for thalidomide and Congenital Rubella Syndrome
| Article | Year |
|---|---|
Causes of birth defects: lessons from history.
Topics: Abnormalities, Drug-Induced; Animals; Australia; Congenital Abnormalities; Female; Fever; History, 2 | 2011 |
3 other studies available for thalidomide and Congenital Rubella Syndrome
| Article | Year |
|---|---|
Correspondence.
Topics: Adenocarcinoma; Adolescent; Adult; Diethylstilbestrol; Female; Humans; Incidental Findings; Limb Def | 2012 |
Regarding how safe is "safe"?
Topics: Adenocarcinoma; Diethylstilbestrol; Female; Humans; Limb Deformities, Congenital; Pregnancy; Rubella | 2013 |
Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Diabetes Mellitus, Type 1; Female; Georgia; H | 1989 |