Page last updated: 2024-11-05

thalidomide and Congenital Foot Deformities

thalidomide has been researched along with Congenital Foot Deformities in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"For a baby with bilateral lower phocomelia, a special "sitting socket" was devised to enable sitting in an upright position."2.36Review of the treatment of thalidomide children with limb defeciency in Great Britain. ( Fletcher, I, 1980)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fletcher, I1
Huenges, E1
Immich, H1
Marquardt, E1
Rompe, G1
Gressmann, C1
Mau, H1
Sharrard, WJ1

Reviews

1 review available for thalidomide and Congenital Foot Deformities

ArticleYear
Review of the treatment of thalidomide children with limb defeciency in Great Britain.
    Clinical orthopaedics and related research, 1980, Issue:148

    Topics: Abnormalities, Drug-Induced; Acromion; Arm; Child; Ectromelia; Foot Deformities, Congenital; Humans;

1980

Other Studies

2 other studies available for thalidomide and Congenital Foot Deformities

ArticleYear
[Documentation and report on thalidomide damage].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1973, Volume: 111, Issue:1

    Topics: Abnormalities, Drug-Induced; Activities of Daily Living; Child; Disability Evaluation; Documentation

1973
Reconstructive surgery of major congenital skeletal deformities of the limbs.
    Developmental medicine and child neurology, 1969, Volume: 11, Issue:2

    Topics: Abnormalities, Drug-Induced; Amputation, Surgical; Child, Preschool; Fibula; Foot Deformities, Conge

1969