thalidomide has been researched along with Coloboma in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Coloboma: Congenital anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smithells, RW | 1 |
| Cullen, JF | 1 |
| Rafuse, EV | 1 |
| Arstikaitis, M | 1 |
| Brent, HP | 1 |
3 other studies available for thalidomide and Coloboma
| Article | Year |
|---|---|
Defects and disabilities of thalidomide children.
Topics: Abnormalities, Drug-Induced; Arm; Child; Coloboma; Ear; Ectromelia; Eye Abnormalities; Heart Defects | 1973 |
Teratogenic agents and thalidomide.
Topics: Abnormalities, Drug-Induced; Coloboma; Eye Abnormalities; Female; Humans; Infant, Newborn; Male; Mic | 1966 |
Ocular findings in thalidomide children.
Topics: Abnormalities, Drug-Induced; Blepharoptosis; Canada; Coloboma; Eye Abnormalities; Female; Humans; In | 1967 |