thalidomide has been researched along with Cleft Spine in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PARTSCH, CJ | 1 |
| INGALLS, TH | 1 |
| KLINGBERG, MA | 1 |
| Wilson, JS | 1 |
| Vallance-Owen, J | 1 |
| McCredie, J | 2 |
| McBride, WG | 1 |
1 review available for thalidomide and Cleft Spine
| Article | Year |
|---|---|
CONGENITAL MALFORMATIONS. CLINICAL AND COMMUNITY CONSIDERATIONS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Achondroplasia; Anencephaly; Cleft Pala | 1965 |
4 other studies available for thalidomide and Cleft Spine
| Article | Year |
|---|---|
[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Congenital Abnormalities; Cryptorchidism; Ear Deformities | 1964 |
Congenital deformities and insulin antagonism.
Topics: Carbohydrate Metabolism; Consanguinity; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; | 1966 |
Embryonic neuropathy. A hypothesis of neural chest injury as the pathogenesis of congenital malformations.
Topics: Abnormalities, Drug-Induced; Animals; Cell Movement; Central Nervous System; Child; Cleft Palate; Co | 1974 |
Some congenital abnormalities: possibly due to embryonic peripheral neuropathy.
Topics: Abnormalities, Drug-Induced; Child; Extremities; Female; Humans; Joints; Limb Deformities, Congenita | 1973 |