thalidomide has been researched along with Cleft Lip in 12 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Cleft Lip: Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KAJII, T | 2 |
| GOTO, M | 1 |
| SALLER, K | 1 |
| FOGH-ANDERSEN, P | 2 |
| Immeyer, F | 1 |
| Jörgensen, G | 1 |
| Lenz, W | 1 |
| Poswillo, DE | 1 |
| Gagliardi, V | 1 |
| Stahl, A | 1 |
| Myers, EN | 1 |
| Stoll, S | 1 |
| Weltschew, A | 1 |
1 review available for thalidomide and Cleft Lip
| Article | Year |
|---|---|
Phenocopies.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anemia, Aplastic; Anorexia Nervosa; Arm; Cleft | 1973 |
11 other studies available for thalidomide and Cleft Lip
| Article | Year |
|---|---|
Cleft lip and palate after thalidomide.
Topics: Cleft Lip; Cleft Palate; Humans; Thalidomide | 1963 |
[ON THE FREQUENCY OF MALFORMATIONS IN BAVARIA. 2].
Topics: Abnormalities, Drug-Induced; Anencephaly; Cleft Lip; Cleft Palate; Clubfoot; Congenital Abnormalitie | 1964 |
[THALIDOMIDE AND CLEFT LIP, JAW AND PALATE].
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Female; Humans; Infant; Infant, Newborn; Pregn | 1965 |
[Cleft lip and palate in thalidomide-induced embryopathies].
Topics: Abnormalities, Drug-Induced; Adult; Arm; Child; Child, Preschool; Cleft Lip; Cleft Palate; Ear Defor | 1967 |
[Abnormalities in the field of otorhinolaryngology. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Chromosome Aberrations | 1972 |
Orofacial malformations.
Topics: Animals; Antimetabolites; Cell Differentiation; Cleft Lip; Cleft Palate; Dermoid Cyst; Eye Neoplasms | 1974 |
[Teratogenic effects induced by N-phthaloylglutamic acid imide in the maxillofacial region].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Animals, Newborn; Cleft Lip; Cleft Pa | 1971 |
Clinical, orthodontic and radiological findings in the jaws and face of children with dysmelia associated with thalidomide-embryopathy.
Topics: Abnormalities, Drug-Induced; Ankylosis; Cephalometry; Child, Preschool; Cleft Lip; Cleft Palate; Fem | 1968 |
Congenital anomaly of the middle and inner ear.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Ear, Inner; Ear, Middle; Humans; Infant; Male; | 1968 |
Thalidomide experience in Japan.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Ectromelia; Female; Humans; Infant, Newborn; J | 1965 |
Thalidomide and congenital cleft deformities.
Topics: Child, Preschool; Cleft Lip; Cleft Palate; Denmark; Ear Deformities, Acquired; Female; Humans; Male; | 1966 |