thalidomide has been researched along with Chylopericardium in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myelofibrosis with myeloid metaplasia (MMM) is uniquely characterized by macroscopic bone marrow stromal changes that are believed to be both reactive and cytokine mediated." | 2.70 | Thalidomide treatment in myelofibrosis with myeloid metaplasia. ( Ansell, SM; Elliott, MA; Geyer, SM; Hook, CC; Levitt, RM; Li, CY; Mesa, RA; Tefferi, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elliott, MA | 1 |
| Mesa, RA | 1 |
| Li, CY | 1 |
| Hook, CC | 1 |
| Ansell, SM | 1 |
| Levitt, RM | 1 |
| Geyer, SM | 1 |
| Tefferi, A | 1 |
1 trial available for thalidomide and Chylopericardium
| Article | Year |
|---|---|
Thalidomide treatment in myelofibrosis with myeloid metaplasia.
Topics: Adult; Aged; Drug Administration Schedule; Female; Hematopoiesis, Extramedullary; Humans; Immunosupp | 2002 |