thalidomide has been researched along with Chronic Pain in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to show the frequency, localisation, intensity, quality and degree of chronic pain in people with thalidomide-induced congenital defects (thalidomide embryopathy) and to investigate the association with biopsychosocial factors more closely." | 8.02 | [Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors]. ( Albus, C; Lüngen, M; Niecke, A; Peters, KM; Pfaff, H; Ramesh, I; Samel, C, 2021) |
| "Lenalidomide is an analog of thalidomide with similar efficacy but improved side-effect profile." | 6.49 | Lenalidomide and thalidomide in the treatment of chronic pain. ( Asher, C; Furnish, T, 2013) |
| "The aim of the study was to show the frequency, localisation, intensity, quality and degree of chronic pain in people with thalidomide-induced congenital defects (thalidomide embryopathy) and to investigate the association with biopsychosocial factors more closely." | 4.02 | [Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors]. ( Albus, C; Lüngen, M; Niecke, A; Peters, KM; Pfaff, H; Ramesh, I; Samel, C, 2021) |
| "Lenalidomide is an analog of thalidomide with similar efficacy but improved side-effect profile." | 2.49 | Lenalidomide and thalidomide in the treatment of chronic pain. ( Asher, C; Furnish, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niecke, A | 1 |
| Ramesh, I | 1 |
| Albus, C | 1 |
| Lüngen, M | 1 |
| Pfaff, H | 1 |
| Samel, C | 1 |
| Peters, KM | 1 |
| Asher, C | 1 |
| Furnish, T | 1 |
1 review available for thalidomide and Chronic Pain
| Article | Year |
|---|---|
Lenalidomide and thalidomide in the treatment of chronic pain.
Topics: Anti-Inflammatory Agents; Chronic Pain; Drug-Related Side Effects and Adverse Reactions; Humans; Imm | 2013 |
1 other study available for thalidomide and Chronic Pain
| Article | Year |
|---|---|
[Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors].
Topics: Chronic Pain; Fetal Diseases; Humans; Prevalence; Surveys and Questionnaires; Thalidomide | 2021 |