thalidomide has been researched along with Cerebral Infarction in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This patient developed acute, multiple cerebral infarctions 5 months into the treatment with thalidomide." | 3.73 | Should we screen patients for inherited thrombophilia before starting thalidomide? ( El-Hajj, II; Harb, MI; Mahfouz, RA; Otrock, ZK; Sawaya, RA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hyakkoku, K | 1 |
| Nakajima, Y | 1 |
| Izuta, H | 1 |
| Shimazawa, M | 1 |
| Yamamoto, T | 1 |
| Shibata, N | 1 |
| Hara, H | 1 |
| Otrock, ZK | 1 |
| Mahfouz, RA | 1 |
| El-Hajj, II | 1 |
| Harb, MI | 1 |
| Sawaya, RA | 1 |
| Wong, EH | 1 |
| Leung, TW | 1 |
| Wong, KS | 1 |
3 other studies available for thalidomide and Cerebral Infarction
| Article | Year |
|---|---|
Thalidomide protects against ischemic neuronal damage induced by focal cerebral ischemia in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Blood Pressure; Cell Death; Cells, Cultu | 2009 |
Should we screen patients for inherited thrombophilia before starting thalidomide?
Topics: Administration, Oral; Aged; Antigens; Cerebral Infarction; Humans; Immunosuppressive Agents; Male; M | 2006 |
Stroke caused by small vessel occlusion in a patient taking etoricoxib and thalidomide.
Topics: Adult; Arthritis, Rheumatoid; Cerebral Infarction; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combin | 2007 |