thalidomide has been researched along with Carotid Stenosis in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found that thalidomide, through its antiinflammatory and antiproliferative effects, significantly inhibits neointimal hyperplasia in balloon-injured rat carotid arteries." | 7.72 | Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery. ( Chae, IH; Choi, DJ; Jeon, SI; Kim, DH; Kim, HS; Koo, BK; Lee, MM; Oh, BH; Park, KW; Park, SJ; Park, YB; Yang, HM; Youn, SW, 2004) |
| "We found that thalidomide, through its antiinflammatory and antiproliferative effects, significantly inhibits neointimal hyperplasia in balloon-injured rat carotid arteries." | 3.72 | Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery. ( Chae, IH; Choi, DJ; Jeon, SI; Kim, DH; Kim, HS; Koo, BK; Lee, MM; Oh, BH; Park, KW; Park, SJ; Park, YB; Yang, HM; Youn, SW, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, SJ | 1 |
| Kim, HS | 1 |
| Yang, HM | 1 |
| Park, KW | 1 |
| Youn, SW | 1 |
| Jeon, SI | 1 |
| Kim, DH | 1 |
| Koo, BK | 1 |
| Chae, IH | 1 |
| Choi, DJ | 1 |
| Oh, BH | 1 |
| Lee, MM | 1 |
| Park, YB | 1 |
1 other study available for thalidomide and Carotid Stenosis
| Article | Year |
|---|---|
Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carotid Arteries; Carotid Stenosis; Catheterizatio | 2004 |