thalidomide has been researched along with Carotid Arteriopathies, Traumatic in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the effect of local administration of thalidomide on neointimal formation after balloon-induced carotid artery injury in rats." | 7.88 | Local delivery of thalidomide to inhibit neointima formation in rat model with artery injury. ( Bai, F; Chang, P; Hu, H; Sun, S; Wang, Q; Wu, Q; Xu, G; Zhang, Q, 2018) |
| "Injured carotid arteries showed marked neointimal hyperplasia, which was significantly inhibited among animals treated with thalidomide or tamoxifen: neointimal/media ratios of 1." | 7.76 | Effectiveness of thalidomide and tamoxifen in preventing neointimal hyperplasia in experimental vascular injury in rats. ( Cordeiro, AC; Dellê, H; Marinotto, DB; Noronha, IL; Santana, AC, 2010) |
| "To observe the effect of local administration of thalidomide on neointimal formation after balloon-induced carotid artery injury in rats." | 3.88 | Local delivery of thalidomide to inhibit neointima formation in rat model with artery injury. ( Bai, F; Chang, P; Hu, H; Sun, S; Wang, Q; Wu, Q; Xu, G; Zhang, Q, 2018) |
| "Injured carotid arteries showed marked neointimal hyperplasia, which was significantly inhibited among animals treated with thalidomide or tamoxifen: neointimal/media ratios of 1." | 3.76 | Effectiveness of thalidomide and tamoxifen in preventing neointimal hyperplasia in experimental vascular injury in rats. ( Cordeiro, AC; Dellê, H; Marinotto, DB; Noronha, IL; Santana, AC, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, S | 1 |
| Zhang, Q | 1 |
| Wang, Q | 1 |
| Wu, Q | 1 |
| Xu, G | 1 |
| Chang, P | 1 |
| Hu, H | 1 |
| Bai, F | 1 |
| Santana, AC | 1 |
| Marinotto, DB | 1 |
| Dellê, H | 1 |
| Cordeiro, AC | 1 |
| Noronha, IL | 1 |
2 other studies available for thalidomide and Carotid Arteriopathies, Traumatic
| Article | Year |
|---|---|
Local delivery of thalidomide to inhibit neointima formation in rat model with artery injury.
Topics: Angiogenesis Inhibitors; Angioplasty; Animals; Carotid Artery Injuries; Disease Models, Animal; Male | 2018 |
Effectiveness of thalidomide and tamoxifen in preventing neointimal hyperplasia in experimental vascular injury in rats.
Topics: Animals; Carotid Arteries; Carotid Artery Injuries; Hyperplasia; Immunohistochemistry; Male; Rats; R | 2010 |