Page last updated: 2024-11-05

thalidomide and Cardiomyopathies

thalidomide has been researched along with Cardiomyopathies in 6 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"High-dose melphalan (HDM) followed by autologous stem cell transplant (ASCT) for light chain amyloidosis (AL) was performed in 31 patients at Oregon Health and Science University between 2005 and 2012."7.80Induction bortezomib in Al amyloidosis followed by high dose melphalan and autologous stem cell transplantation: a single institution retrospective study. ( Abar, F; Dibb, J; Dibb, W; Frires, R; Heitner, SB; Kovacsovics, T; Maziarz, RT; Meyers, G; Perez-Avraham, G; Scott, EC; Smith, SD; Stentz, A, 2014)
"High-dose melphalan (HDM) followed by autologous stem cell transplant (ASCT) for light chain amyloidosis (AL) was performed in 31 patients at Oregon Health and Science University between 2005 and 2012."3.80Induction bortezomib in Al amyloidosis followed by high dose melphalan and autologous stem cell transplantation: a single institution retrospective study. ( Abar, F; Dibb, J; Dibb, W; Frires, R; Heitner, SB; Kovacsovics, T; Maziarz, RT; Meyers, G; Perez-Avraham, G; Scott, EC; Smith, SD; Stentz, A, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Khandkar, C1
Vaidya, K1
Penglase, R1
Cai, K1
Shin, JS1
Hunyor, I1
Keech, A1
McGill, N1
Scott, EC1
Heitner, SB1
Dibb, W1
Meyers, G1
Smith, SD1
Abar, F1
Kovacsovics, T1
Perez-Avraham, G1
Stentz, A1
Frires, R1
Dibb, J1
Maziarz, RT1
De Lazzari, M1
Fedrigo, M1
Migliore, F1
Cianci, A1
Cacciavillani, L1
Tarantini, G1
Giorgi, B1
Iliceto, S1
Thiene, G1
Valente, M1
Angelini, A1
Adami, F1
Perazzolo Marra, M1
Chan, LL1
Lim, CP1
Lim, CH1
Tan, TE1
Sim, D1
Sivathasan, C1
Desport, E1
Moumas, E1
Abraham, J1
Delbès, S1
Lacotte-Thierry, L1
Touchard, G1
Fermand, JP1
Bridoux, F1
Jaccard, A1
Homburger, F1
Bajusz, E1

Reviews

1 review available for thalidomide and Cardiomyopathies

ArticleYear
[Current treatment of AL amyloidosis].
    Nephrologie & therapeutique, 2011, Volume: 7, Issue:6

    Topics: Amyloid; Amyloidosis; Biomarkers; Boronic Acids; Bortezomib; Cardiomyopathies; Consensus Development

2011

Other Studies

5 other studies available for thalidomide and Cardiomyopathies

ArticleYear
Rare case of infiltrative cardiomyopathy secondary to scleromyxoedema.
    Internal medicine journal, 2020, Volume: 50, Issue:1

    Topics: Adult; Cardiomyopathies; Female; Humans; Immunoglobulins, Intravenous; Magnetic Resonance Imaging; P

2020
Induction bortezomib in Al amyloidosis followed by high dose melphalan and autologous stem cell transplantation: a single institution retrospective study.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:5

    Topics: Adult; Aged; Amyloidogenic Proteins; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bo

2014
Nonamyloidotic Light Chain Cardiomyopathy: The Arrhythmogenic Magnetic Resonance Pattern.
    Circulation, 2016, Apr-05, Volume: 133, Issue:14

    Topics: Bortezomib; Cardiomyopathies; Combined Modality Therapy; Defibrillators, Implantable; Dexamethasone;

2016
Novel Use of Thalidomide in Recurrent Gastrointestinal Tract Bleeding in Patients with Left Ventricular Assist Devices: A Case Series.
    Heart, lung & circulation, 2017, Volume: 26, Issue:10

    Topics: Aged; Angiogenesis Inhibitors; Cardiomyopathies; Dose-Response Relationship, Drug; Gastrointestinal

2017
New models of human disease in Syrian hamsters.
    JAMA, 1970, Apr-27, Volume: 212, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Animals; Cardiomyopathies; Cricetinae; Cyclamates; Disease Models,

1970