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thalidomide and Cardiac Septal Defect

thalidomide has been researched along with Cardiac Septal Defect in 5 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SCHUMACHER, H1
ODUNJO, F1
JORGENSEN, MB1
KRISTENSEN, HK1
BUCH, NH1
ROSENDAL, T1
Palmer, AK1
Vickers, TH1

Other Studies

5 other studies available for thalidomide and Cardiac Septal Defect

ArticleYear
[PERSISTENT TRUNCUS ARTERIOSUS COMMUNIS IN SO-CALLED THALIDOMIDE EMBRYOPATHY].
    Deutsche medizinische Wochenschrift (1946), 1963, Sep-06, Volume: 88

    Topics: Ductus Arteriosus; Ectromelia; Fetal Diseases; Heart Septal Defects; Heart Septal Defects, Ventricul

1963
THALIDOMIDE-INDUCED APLASIA OF THE INNER EAR.
    The Journal of laryngology and otology, 1964, Volume: 78

    Topics: Abnormalities, Drug-Induced; Ear Deformities, Acquired; Ear, External; Ear, Inner; Facial Paralysis;

1964
APLASIA-HYPOPLASIA OF THE OTIC LABYRINTH AFTER THALIDOMIDE.
    Acta radiologica: diagnosis, 1965, Volume: 3

    Topics: Abnormalities, Drug-Induced; Cochlear Nerve; Ear Canal; Ear Deformities, Acquired; Ear, External; Ea

1965
Problems associated with the screening of drugs for possible teratogenic activity.
    Experimental embryology and teratology, 1974, Volume: 1, Issue:0

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Aspirin; Dose-Response Rela

1974
The cardiovascular malformations in the rabbit thalidomide embryopathy.
    British journal of experimental pathology, 1968, Volume: 49, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aorta; Bronchial Arteries; Cardiovascular Abnormalities; Cardi

1968