thalidomide has been researched along with Cardiac Remodeling, Ventricular in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis." | 7.73 | Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006) |
| "Although thalidomide had no effect on cardiac function, our results suggest that intervention with thalidomide may have beneficial effects in post-MI HF by attenuating collagen accumulation and development of myocardial fibrosis." | 3.73 | Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats. ( Attramadal, H; Aukrust, P; Bjørnerheim, R; Frøland, SS; Oie, E; Ueland, T; Vinge, LE; Wang, JE; Yndestad, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mann, DL | 1 |
| Yndestad, A | 1 |
| Vinge, LE | 1 |
| Bjørnerheim, R | 1 |
| Ueland, T | 1 |
| Wang, JE | 1 |
| Frøland, SS | 1 |
| Attramadal, H | 1 |
| Aukrust, P | 1 |
| Oie, E | 1 |
1 review available for thalidomide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Innate immunity and the failing heart: the cytokine hypothesis revisited.
Topics: Adaptive Immunity; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Autoantibodies; Autoim | 2015 |
1 other study available for thalidomide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats.
Topics: Animals; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hydroxyprolin | 2006 |