thalidomide has been researched along with Carcinoma, Lewis Lung in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has recently been shown to be useful in the treatment of multiple myeloma and may also be useful in the treatment of other hematological malignancies." | 3.71 | S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice. ( Anderson, KC; Birsner, AE; D'Amato, RJ; LeBlanc, R; Lentzsch, S; Rogers, MS; Shah, JH; Treston, AM, 2002) |
| "Lewis lung carcinoma was successfully implanted in 32 C57BL/6 mice, which were then randomly divided into the model control group, the Thalidomide group, the TPs group and the TPs combined with Thalidomide group." | 1.38 | [Effects of tea polyphenols on the expression of NF-κB, COX-2 and survivin in Lewis lung carcinoma xenografts in C57BL/6 mice]. ( Chen, X; Hou, L; Li, L; Liu, W; Lu, H; Wang, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Chen, X | 1 |
| Hou, L | 1 |
| Li, L | 1 |
| Lu, H | 1 |
| Liu, W | 1 |
| Kim, DH | 1 |
| Choe, YS | 1 |
| Jung, KH | 1 |
| Lee, KH | 1 |
| Choi, Y | 1 |
| Kim, BT | 1 |
| Lentzsch, S | 1 |
| Rogers, MS | 1 |
| LeBlanc, R | 1 |
| Birsner, AE | 1 |
| Shah, JH | 1 |
| Treston, AM | 1 |
| Anderson, KC | 1 |
| D'Amato, RJ | 1 |
3 other studies available for thalidomide and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
[Effects of tea polyphenols on the expression of NF-κB, COX-2 and survivin in Lewis lung carcinoma xenografts in C57BL/6 mice].
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis L | 2012 |
Synthesis and evaluation of 4-[(18)F]fluorothalidomide for the in vivo studies of angiogenesis.
Topics: Animals; Carcinoma, Lewis Lung; Endothelial Cells; Humans; Isotope Labeling; Metabolic Clearance Rat | 2006 |
S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice.
Topics: 3T3 Cells; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Burkitt Lymphoma; Carcinoma, Lew | 2002 |