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thalidomide and Carcinoma, Ehrlich Tumor

thalidomide has been researched along with Carcinoma, Ehrlich Tumor in 10 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.

Research Excerpts

ExcerptRelevanceReference
" This dosage form permits the prolonged drug release."1.39Evaluation of the effects of thalidomide-loaded biodegradable devices in solid Ehrlich tumor. ( Dantas Cassali, G; Ligorio Fialho, S; Maria de Souza, C; Pereira, BG; Silva-Cunha, A, 2013)
"Thalidomide has been reported to have anti-angiogenic and antimetastatic effects."1.36Effect of thalidomide dithiocarbamate analogs on the intercellular adhesion molecule-1 expression. ( Abdou, BY; Agwa, HS; Guirgis, AA; Mohamed, AS; Talaat, RM; Zahran, MA, 2010)
"Clotrimazole was the most potent antiangiogenic compound and the agent capable of inhibiting tumor growth."1.32Differential effects of antiangiogenic compounds in neovascularization, leukocyte recruitment, VEGF production, and tumor growth in mice. ( Andrade, SP; Barcelos, LS; Belo, AV; Ferreira, MA; Teixeira, MM, 2004)
"Thalidomide did not inhibit dehydrogenase activity or growth of Ehrlich ascites tumor cells in agar."1.24THALIDOMIDE: EFFECTS ON EHRLICH ASCITES TUMOR CELLS IN VITRO. ( DIPAOLO, JA; WENNER, CE, 1964)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zahran, MA2
Salem, TA1
Samaka, RM1
Agwa, HS2
Awad, AR1
Guirgis, AA1
Mohamed, AS1
Talaat, RM1
Abdou, BY1
Pereira, BG1
Ligorio Fialho, S1
Maria de Souza, C1
Dantas Cassali, G1
Silva-Cunha, A1
JURET, P1
AUBERT, C1
DIPAOLO, JA2
PAGNINI, G1
DICARLO, R1
WENNER, CE1
Belo, AV2
Barcelos, LS1
Teixeira, MM1
Ferreira, MA2
Andrade, SP2
Bosco, AA1
Machado, RD1
De, AU1
Pal, D1

Other Studies

10 other studies available for thalidomide and Carcinoma, Ehrlich Tumor

ArticleYear
Design, synthesis and antitumor evaluation of novel thalidomide dithiocarbamate and dithioate analogs against Ehrlich ascites carcinoma-induced solid tumor in Swiss albino mice.
    Bioorganic & medicinal chemistry, 2008, Nov-15, Volume: 16, Issue:22

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Ehrlich Tumor; Cat

2008
Effect of thalidomide dithiocarbamate analogs on the intercellular adhesion molecule-1 expression.
    International immunopharmacology, 2010, Volume: 10, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Adhesion; Female; Intercel

2010
Evaluation of the effects of thalidomide-loaded biodegradable devices in solid Ehrlich tumor.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:2

    Topics: Absorbable Implants; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Antineoplastic

2013
[Absence of carcinostatic effect of thalidomide with respect to 2 grafted tumors].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Jun-10, Volume: 157

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Neoplasms, Experimental; Thalidomide

1963
IN VITRO TEST SYSTEMS FOR CANCER CHEMOTHERAPY. II. CORRELATION OF IN VITRO INHIBITION OF DEHYDROGENASE AND GROWTH WITH IN VIVO INHIBITION OF EHRLICH ASCITES TUMOR.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 114

    Topics: Animals; Antineoplastic Agents; Arsenicals; Carbamates; Carcinoma; Carcinoma, Ehrlich Tumor; Colchic

1963
[TREATMENT OF EXPERIMENTAL TUMORS WITH THALIDOMIDE].
    Bollettino della Societa italiana di biologia sperimentale, 1963, Nov-30, Volume: 39

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Mice; Multiple Myeloma; Neoplasms; Neoplasms, Experime

1963
THALIDOMIDE: EFFECTS ON EHRLICH ASCITES TUMOR CELLS IN VITRO.
    Science (New York, N.Y.), 1964, Jun-26, Volume: 144, Issue:3626

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Folic Acid; In Vitro Techniques; Metabolism; Niaci

1964
Differential effects of antiangiogenic compounds in neovascularization, leukocyte recruitment, VEGF production, and tumor growth in mice.
    Cancer investigation, 2004, Volume: 22, Issue:5

    Topics: Acetylglucosaminidase; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Carcinoma, Ehrlic

2004
Differential effects of thalidomide on angiogenesis and tumor growth in mice.
    Inflammation, 2001, Volume: 25, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Ehrlich Tumor; Granuloma, Foreign-Body; Male; Mice; Neo

2001
Possible antineoplastic agents I.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Mice; Nitro Compounds; Phthalimides; Pyrid

1975