thalidomide has been researched along with Capillary Leak Syndrome in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Capillary Leak Syndrome: A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this report, we describe a case of systemic capillary leak syndrome in which serum isoform D of vascular endothelial growth factor was elevated." | 1.43 | Isoform D of vascular endothelial growth factor in systemic capillary leak syndrome: a case report. ( Hashimoto, A; Horiguchi, H; Ibata, S; Iyama, S; Jomen, W; Kamihara, Y; Kato, J; Kobune, M; Miyanishi, K; Murase, K; Ono, K; Sato, T; Sato, Y; Takada, K; Takimoto, R; Tatekoshi, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibata, S | 1 |
| Sato, T | 1 |
| Takada, K | 1 |
| Tatekoshi, A | 1 |
| Hashimoto, A | 1 |
| Kamihara, Y | 1 |
| Jomen, W | 1 |
| Horiguchi, H | 1 |
| Ono, K | 1 |
| Murase, K | 1 |
| Iyama, S | 1 |
| Miyanishi, K | 1 |
| Sato, Y | 1 |
| Takimoto, R | 1 |
| Kobune, M | 1 |
| Kato, J | 1 |
| Tageja, N | 1 |
| Rechner, I | 1 |
| Brito-Babapulle, F | 1 |
| Fielden, J | 1 |
| Staak, JO | 1 |
| Glossmann, JP | 1 |
| Esser, JM | 1 |
| Diehl, V | 1 |
| Mietz, H | 1 |
| Josting, A | 1 |
4 other studies available for thalidomide and Capillary Leak Syndrome
| Article | Year |
|---|---|
Isoform D of vascular endothelial growth factor in systemic capillary leak syndrome: a case report.
Topics: Adult; Angiogenesis Inhibitors; Biomarkers; Capillary Leak Syndrome; Humans; Hypotension; Male; Prot | 2016 |
POEMS syndrome, congestive heart failure and thalidomide -food for thought.
Topics: Capillary Leak Syndrome; Dexamethasone; Drug Therapy, Combination; Heart Failure; Humans; Inflammati | 2010 |
Systemic capillary leak syndrome after granulocyte colony-stimulating factor (G-CSF).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capillary Leak Syndrome; Combined Modality Th | 2003 |
Thalidomide for systemic capillary leak syndrome.
Topics: Capillary Leak Syndrome; Capillary Permeability; Compartment Syndromes; Humans; Immunosuppressive Ag | 2003 |