thalidomide has been researched along with Canine Diseases in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate thalidomide as an adjuvant treatment for canine haemangiosarcoma." | 7.88 | Does thalidomide prolong survival in dogs with splenic haemangiosarcoma? ( Bray, JP; Cave, N; Munday, JS; Orbell, G, 2018) |
| "To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation." | 7.72 | Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004) |
| "The aim of the study was to evaluate the incidence of adverse events (AEs) in female dogs diagnosed with advanced clinical stage mammary gland neoplasms following treatment with thalidomide." | 5.43 | Absence of significant adverse events following thalidomide administration in bitches diagnosed with mammary gland carcinomas. ( Amorim, RL; Camargo Nunes, F; Carneiro, RA; Cassali, GD; de Campos, CB; Fialho Ligório, S; Lavalle, GE, 2016) |
| "To investigate thalidomide as an adjuvant treatment for canine haemangiosarcoma." | 3.88 | Does thalidomide prolong survival in dogs with splenic haemangiosarcoma? ( Bray, JP; Cave, N; Munday, JS; Orbell, G, 2018) |
| "To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation." | 3.72 | Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004) |
| "The aim of the study was to evaluate the incidence of adverse events (AEs) in female dogs diagnosed with advanced clinical stage mammary gland neoplasms following treatment with thalidomide." | 1.43 | Absence of significant adverse events following thalidomide administration in bitches diagnosed with mammary gland carcinomas. ( Amorim, RL; Camargo Nunes, F; Carneiro, RA; Cassali, GD; de Campos, CB; Fialho Ligório, S; Lavalle, GE, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bray, JP | 1 |
| Orbell, G | 1 |
| Cave, N | 1 |
| Munday, JS | 1 |
| Polton, G | 1 |
| Finotello, R | 1 |
| Sabattini, S | 2 |
| Rossi, F | 2 |
| Laganga, P | 1 |
| Vasconi, ME | 1 |
| Barbanera, A | 1 |
| Stiborova, K | 1 |
| Rohrer Bley, C | 1 |
| Marconato, L | 2 |
| Vascellari, M | 1 |
| Togni, A | 1 |
| Rütten, M | 1 |
| Bley, CR | 1 |
| Hurter, K | 1 |
| de Campos, CB | 1 |
| Lavalle, GE | 1 |
| Fialho Ligório, S | 1 |
| Camargo Nunes, F | 1 |
| Carneiro, RA | 1 |
| Amorim, RL | 1 |
| Cassali, GD | 1 |
| Farese, JP | 1 |
| Fox, LE | 1 |
| Detrisac, CJ | 1 |
| Van Gilder, JM | 1 |
| Roberts, SL | 1 |
| Baldwin, JM | 1 |
6 other studies available for thalidomide and Canine Diseases
| Article | Year |
|---|---|
Does thalidomide prolong survival in dogs with splenic haemangiosarcoma?
Topics: Angiogenesis Inhibitors; Animals; Chemotherapy, Adjuvant; Dog Diseases; Dogs; Female; Hemangiosarcom | 2018 |
Survival analysis of dogs with advanced primary lung carcinoma treated by metronomic cyclophosphamide, piroxicam and thalidomide.
Topics: Administration, Metronomic; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Comb | 2018 |
The impact of toceranib, piroxicam and thalidomide with or without hypofractionated radiation therapy on clinical outcome in dogs with inflammatory mammary carcinoma.
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Dog Diseases; Dogs; Drug Therapy, Combina | 2018 |
Metastasized Leydig cell tumor in a dog.
Topics: Administration, Metronomic; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Che | 2015 |
Absence of significant adverse events following thalidomide administration in bitches diagnosed with mammary gland carcinomas.
Topics: Animals; Carcinoma; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, | 2016 |
Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice.
Topics: Angiogenesis Inhibitors; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Dose-Response Relationship | 2004 |