thalidomide has been researched along with Cancer of Gastrointestinal Tract in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracerebral plasmacytoma is an extremely rare disease for which no treatment protocol has been established." | 5.46 | Metastatic Intracerebral Plasmacytoma Treated with Radiation and Thalidomide, Dexamethasone with Cyclophosphamide Chemotherapy. ( Kang, SH; Kim, TS; Ko, SJ; Park, KJ, 2017) |
| " In addition, antiangiogenic agents may be valuable for long-term administration to maintain tumor dormancy, because drug resistance does not develop and these agents have a sustained effect." | 2.40 | Antiangiogenic therapy for liver metastasis of gastrointestinal malignancies. ( Baba, M; Kanai, T; Konno, H; Nakamura, S; Tanaka, T, 1999) |
| "Intracerebral plasmacytoma is an extremely rare disease for which no treatment protocol has been established." | 1.46 | Metastatic Intracerebral Plasmacytoma Treated with Radiation and Thalidomide, Dexamethasone with Cyclophosphamide Chemotherapy. ( Kang, SH; Kim, TS; Ko, SJ; Park, KJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Lier, S | 1 |
| Sellmer, A | 1 |
| Orben, F | 1 |
| Heinzlmeir, S | 1 |
| Krauß, L | 1 |
| Schneeweis, C | 1 |
| Hassan, Z | 1 |
| Schneider, C | 1 |
| Patricia Gloria Schäfer, A | 1 |
| Pongratz, H | 1 |
| Engleitner, T | 1 |
| Öllinger, R | 1 |
| Kuisl, A | 1 |
| Bassermann, F | 1 |
| Schlag, C | 1 |
| Kong, B | 1 |
| Dove, S | 1 |
| Kuster, B | 1 |
| Rad, R | 1 |
| Reichert, M | 1 |
| Wirth, M | 1 |
| Saur, D | 1 |
| Mahboobi, S | 1 |
| Schneider, G | 1 |
| Kim, TS | 1 |
| Ko, SJ | 1 |
| Park, KJ | 1 |
| Kang, SH | 1 |
| Prince, SK | 1 |
| Forgeson, G | 1 |
| Tassinari, D | 1 |
| Santelmo, C | 1 |
| Tombesi, P | 1 |
| Sartori, S | 1 |
| Pregun, I | 1 |
| Bodoky, G | 1 |
| Rácz, K | 1 |
| Tulassay, Z | 1 |
| Wilkes, EA | 1 |
| Freeman, JG | 1 |
| Konno, H | 1 |
| Tanaka, T | 1 |
| Baba, M | 1 |
| Kanai, T | 1 |
| Nakamura, S | 1 |
2 reviews available for thalidomide and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
[Carcinoid tumors].
Topics: 3-Iodobenzylguanidine; Antineoplastic Agents; Biomarkers, Tumor; Bronchial Neoplasms; Carcinoid Tumo | 2010 |
Antiangiogenic therapy for liver metastasis of gastrointestinal malignancies.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Endothelial Growth Factors; Female; Gas | 1999 |
1 trial available for thalidomide and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Thalidomide in the treatment of cancer cachexia.
Topics: Aged; Angiogenesis Inhibitors; Anorexia; Cachexia; Drug Monitoring; Female; Gastrointestinal Neoplas | 2008 |
4 other studies available for thalidomide and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, | 2022 |
Metastatic Intracerebral Plasmacytoma Treated with Radiation and Thalidomide, Dexamethasone with Cyclophosphamide Chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cranial Irradiation; Cyclophosphami | 2017 |
Bleeding from gastrointestinal tract recurrence of non-seminomatous germ cell tumour testis, showing temporary response to gemcitabine and oxaliplatin chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Gastrointestinal Hemorrhage; G | 2013 |
Thalidomide: an effective anabolic agent in gastrointestinal cancer cachexia.
Topics: Anabolic Agents; Cachexia; Gastrointestinal Neoplasms; Humans; Thalidomide | 2006 |