Page last updated: 2024-11-05

thalidomide and Burns

thalidomide has been researched along with Burns in 1 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide treatment decreased TNF and IL-1 significantly in both experimental groups at both the points (P<0."1.35Thalidomide decreases the plasma levels of IL-1 and TNF following burn injury: is it a new drug for modulation of systemic inflammatory response. ( Eski, M; Ifran, A; Sahin, I; Sengezer, M; Serdar, M, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eski, M1
Sahin, I1
Sengezer, M1
Serdar, M1
Ifran, A1

Other Studies

1 other study available for thalidomide and Burns

ArticleYear
Thalidomide decreases the plasma levels of IL-1 and TNF following burn injury: is it a new drug for modulation of systemic inflammatory response.
    Burns : journal of the International Society for Burn Injuries, 2008, Volume: 34, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Drug Evaluation, Preclinical; Interleukin-1

2008