thalidomide has been researched along with Brain Disorders in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has proven useful for patients with Langerhans cell histiocytosis of the skin and/or bone." | 2.43 | Drug therapy for the treatment of Langerhans cell histiocytosis. ( McClain, KL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| do Prado, AD | 1 |
| Schmoeller, D | 1 |
| Bisi, MC | 1 |
| Piovesan, DM | 1 |
| Dias, FS | 1 |
| Staub, HL | 1 |
| LAIDLAW, J | 1 |
| CATLING, J | 1 |
| McClain, KL | 1 |
| Pandey, R | 1 |
| Patel, A | 1 |
| Shah, S | 1 |
| Patel, KM | 1 |
| Shah, PM | 1 |
| Shukla, SN | 1 |
| Parikh, BJ | 1 |
| Anand, A | 1 |
| Talati, SS | 1 |
| Panchal, H | 1 |
| Parikh, S | 1 |
| Thrutthel, S | 1 |
| Sohlbach, K | 1 |
| Heinze, S | 1 |
| Shiratori, K | 1 |
| Sure, U | 1 |
| Pagenstecher, A | 1 |
| Neubauer, A | 1 |
| Murphy, R | 1 |
| Mohr, P | 1 |
| Plum, P | 1 |
1 review available for thalidomide and Brain Disorders
| Article | Year |
|---|---|
Drug therapy for the treatment of Langerhans cell histiocytosis.
Topics: Anti-Inflammatory Agents; Antimetabolites; Brain Diseases; Cell Proliferation; Cladribine; Cytarabin | 2005 |
6 other studies available for thalidomide and Brain Disorders
| Article | Year |
|---|---|
Scleromyxedema with monoclonal gammopathy and neurological involvement: recovery from coma after plasmapheresis?
Topics: Brain Diseases; Coma; Humans; Immunosuppressive Agents; Male; Melphalan; Middle Aged; Myeloablative | 2012 |
AN E.E.G. ASSESSMENT OF ENCEPHALOPATHY IN PARKINSONISM.
Topics: Brain Diseases; Drug Therapy; Electroencephalography; Geriatrics; Parkinsonian Disorders; Surgical P | 1964 |
A rare complication in a case of multiple myeloma on therapy with thalidomide and dexamethasone--reversible posterior lobe leukoencephalopathy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Diseases; Dexamethasone; Female; Humans | 2006 |
Encephalopathy in a patient after long-term treatment with thalidomide.
Topics: Angiogenesis Inhibitors; Brain Diseases; Drug Administration Schedule; Humans; Magnetic Resonance Im | 2006 |
Two congenital neurological abnormalities caused by thalidomide.
Topics: Abnormalities, Drug-Induced; Adolescent; Brain Diseases; Female; Humans; Ophthalmoplegia; Thalidomid | 1977 |
[Human genetic perspectives. Antenatal and perinatal exogenous disease causes].
Topics: Abnormalities, Drug-Induced; Asphyxia Neonatorum; Brain Diseases; Genetics, Medical; Humans; Infant, | 1966 |