Page last updated: 2024-11-05

thalidomide and Brain Dead

thalidomide has been researched along with Brain Dead in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide treatment also induced a significant decrease in the expression of ET-1 (1."5.72Thalidomide modulates renal inflammation induced by brain death experimental model. ( Andraus, W; Brasil, S; de Moraes, EL; de Oliveira-Braga, KA; Dellê, H; Dos Santos, MJ; Feliciano, R; Figueiredo, EG; Nepomuceno, NA; Neri, LHM; Pêgo-Fernandes, PM; Pepineli, R; Ruiz, LM; Sala, ACG; Santana, AC; Schust, AS; Silva, FMO, 2022)
"Thalidomide treatment also induced a significant decrease in the expression of ET-1 (1."1.72Thalidomide modulates renal inflammation induced by brain death experimental model. ( Andraus, W; Brasil, S; de Moraes, EL; de Oliveira-Braga, KA; Dellê, H; Dos Santos, MJ; Feliciano, R; Figueiredo, EG; Nepomuceno, NA; Neri, LHM; Pêgo-Fernandes, PM; Pepineli, R; Ruiz, LM; Sala, ACG; Santana, AC; Schust, AS; Silva, FMO, 2022)
"Thalidomide treatment significantly reduced serum levels of hepatic enzymes and TNF-α, IL-1-β, and IL-6."1.62Immunomodulatory effects of thalidomide in an experimental brain death liver donor model. ( Andraus, W; Brasil, S; de Moraes, EL; de Oliveira-Braga, KA; de Sá Lima, L; Degaspari, S; Dellê, H; Figueiredo, EG; Nepomuceno, NA; Pêgo-Fernandes, PM; Pepineli, R; Ruiz, LM; Santana, AC; Scavone, C; Silva, FMO; Solla, DJF; Tullius, SG, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Santana, AC2
Andraus, W2
Silva, FMO2
Dellê, H2
Pepineli, R2
de Moraes, EL2
Scavone, C1
de Sá Lima, L1
Degaspari, S1
Brasil, S2
Solla, DJF1
Ruiz, LM2
de Oliveira-Braga, KA2
Nepomuceno, NA2
Pêgo-Fernandes, PM2
Tullius, SG1
Figueiredo, EG2
Sala, ACG1
Schust, AS1
Neri, LHM1
Feliciano, R1
Dos Santos, MJ1

Other Studies

2 other studies available for thalidomide and Brain Dead

ArticleYear
Immunomodulatory effects of thalidomide in an experimental brain death liver donor model.
    Scientific reports, 2021, 09-28, Volume: 11, Issue:1

    Topics: Allografts; Animals; Brain Death; Disease Models, Animal; Graft Rejection; Humans; Liver; Liver Tran

2021
Thalidomide modulates renal inflammation induced by brain death experimental model.
    Transplant immunology, 2022, Volume: 75

    Topics: Animals; Brain Death; Creatinine; Cytokines; Disease Models, Animal; Inflammation; Interleukin-6; Ma

2022