thalidomide has been researched along with Brachial Paresis in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Childhood tuberculous meningitis is associated with serious long-term sequelae, including mental retardation, behavior disturbances, and motor handicap." | 2.71 | Adjunctive thalidomide therapy for childhood tuberculous meningitis: results of a randomized study. ( Hanekom, WA; Haslett, PA; Kaplan, G; Schoeman, JF; Springer, P; Swanevelder, S; van Rensburg, AJ, 2004) |
| "Cranial nerve palsy/paresis was only seen in HFM and thalidomide-induced malformations." | 1.30 | Teratological studies on craniofacial malformations. ( Jacobsson, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourcade, C | 1 |
| Mauboussin, JM | 1 |
| Lechiche, C | 1 |
| Lavigne, JP | 1 |
| Sotto, A | 1 |
| Schoeman, JF | 1 |
| Springer, P | 1 |
| van Rensburg, AJ | 1 |
| Swanevelder, S | 1 |
| Hanekom, WA | 1 |
| Haslett, PA | 1 |
| Kaplan, G | 1 |
| Jacobsson, C | 1 |
1 trial available for thalidomide and Brachial Paresis
| Article | Year |
|---|---|
Adjunctive thalidomide therapy for childhood tuberculous meningitis: results of a randomized study.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antitubercular Agents; Chemotherapy, Adjuvant; Ch | 2004 |
2 other studies available for thalidomide and Brachial Paresis
| Article | Year |
|---|---|
Thalidomide in the treatment of immune reconstitution inflammatory syndrome in HIV patients with neurological tuberculosis.
Topics: AIDS-Related Opportunistic Infections; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active | 2014 |
Teratological studies on craniofacial malformations.
Topics: Alkaline Phosphatase; Aminopropionitrile; Amniotic Fluid; Animals; Branchial Region; Cartilage; Clef | 1997 |