Page last updated: 2024-11-05

thalidomide and Besnier-Boeck Disease

thalidomide has been researched along with Besnier-Boeck Disease in 36 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide use in cutaneous sarcoidosis is based on data from small case series or case reports."9.19A randomized, investigator-masked, double-blind, placebo-controlled trial on thalidomide in severe cutaneous sarcoidosis. ( Chevrant-Breton, J; Chosidow, O; Cosnes, A; D'Incan, M; Desseaux, K; Droitcourt, C; Dupin, N; Dupuy, A; Joly, P; Juillard, C; Lacour, JP; Lebrun-Vignes, B; Misery, L; Porcher, R; Revuz, J; Rybojad, M; Sassolas, B; Tazi, A; Valeyre, D, 2014)
"Limited data report thalidomide improves cutaneous sarcoidosis; no benefit has been reported for pulmonary localization."9.16Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids. ( Antonelli, A; Barachini, P; Calabrese, R; Carpi, A; Cei, G; Cristofani, R; Fazzi, P; Manni, E; Piazza, S; Siciliano, G, 2012)
"Thalidomide efficacy and tolerance in patients with cutaneous sarcoidosis merits further evaluation in a controlled trial."9.11Treatment of cutaneous sarcoidosis with thalidomide. ( Cordoliani, F; Dupuy, A; Lebbé, C; Morel, P; Nguyen, YT; Rybojad, M; Vignon-Pennamen, MD, 2004)
"Thalidomide was an effective form of treatment for chronic cutaneous sarcoidosis."9.10Thalidomide for chronic sarcoidosis. ( Baughman, RP; Judson, MA; Lower, EE; Moller, DR; Teirstein, AS, 2002)
"Data from ten patients with sarcoidosis treated with thalidomide between January 1998 and March 1999 were collected from delivery authorizations and analyzed."7.71[Sarcoidosis: thalidomide treatment in ten patients]. ( Bressieux, JM; Cosnes, A; Estines, O; Revuz, J; Roujeau, JC; Wolkenstein, P, 2001)
"A patient with sarcoidosis was treated with thalidomide for disfiguring and painful steroid unresponsive sarcoidal granulomas of the skin."7.70Disfiguring cutaneous manifestation of sarcoidosis treated with thalidomide: a case report. ( Koblenzer, PS; Lee, JB, 1998)
" Because administration of low doses of thalidomide has been successful in treating other inflammatory diseases, it was used in a patient with systemic sarcoidosis who was unresponsive to corticosteroids and in a patient with pulmonary sarcoidosis, in whom Kaposi's sarcoma developed after a course of corticosteroid therapy."7.69Treatment of cutaneous and pulmonary sarcoidosis with thalidomide. ( Bonaccorsi, P; Calvieri, S; Carlesimo, M; Giustini, S; Rossi, A, 1995)
"Thalidomide has a different toxicity profile than corticosteroids or immunosuppressives."6.42Newer therapies for cutaneous sarcoidosis: the role of thalidomide and other agents. ( Baughman, RP; Lower, EE, 2004)
"Thalidomide was given to 2 patients with EOS (a 16-year-old girl and an 8-year-old boy) at an initial dosage of 2 mg/kg/day, and the dosage was increased if necessary."5.36Thalidomide dramatically improves the symptoms of early-onset sarcoidosis/Blau syndrome: its possible action and mechanism. ( Manki, A; Morishima, T; Takemoto, K; Tsuge, M; Yamamoto, M; Yashiro, M; Yasui, K, 2010)
"Thalidomide is an immunomodulatory agent that acts to inhibit production of tumor-necrosis factor-alpha (TNF-alpha), an important mediator in CNS inflammation, by enhancing TNF-alpha mRNA degradation."5.34Thalidomide for acute treatment of neurosarcoidosis. ( Hammond, ER; Kaplin, AI; Kerr, DA, 2007)
"Thalidomide was effective for muscular, cutaneous, and pulmonary involvement in our patient."5.32Successful treatment of muscle sarcoidosis with thalidomide. ( Lochmüller, H; Meindl, T; Müller-Felber, W; Schlotter-Weigel, B; Walter, MC, 2003)
"Thalidomide use in cutaneous sarcoidosis is based on data from small case series or case reports."5.19A randomized, investigator-masked, double-blind, placebo-controlled trial on thalidomide in severe cutaneous sarcoidosis. ( Chevrant-Breton, J; Chosidow, O; Cosnes, A; D'Incan, M; Desseaux, K; Droitcourt, C; Dupin, N; Dupuy, A; Joly, P; Juillard, C; Lacour, JP; Lebrun-Vignes, B; Misery, L; Porcher, R; Revuz, J; Rybojad, M; Sassolas, B; Tazi, A; Valeyre, D, 2014)
"Limited data report thalidomide improves cutaneous sarcoidosis; no benefit has been reported for pulmonary localization."5.16Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids. ( Antonelli, A; Barachini, P; Calabrese, R; Carpi, A; Cei, G; Cristofani, R; Fazzi, P; Manni, E; Piazza, S; Siciliano, G, 2012)
"Thalidomide efficacy and tolerance in patients with cutaneous sarcoidosis merits further evaluation in a controlled trial."5.11Treatment of cutaneous sarcoidosis with thalidomide. ( Cordoliani, F; Dupuy, A; Lebbé, C; Morel, P; Nguyen, YT; Rybojad, M; Vignon-Pennamen, MD, 2004)
"Thalidomide was an effective form of treatment for chronic cutaneous sarcoidosis."5.10Thalidomide for chronic sarcoidosis. ( Baughman, RP; Judson, MA; Lower, EE; Moller, DR; Teirstein, AS, 2002)
"The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate."4.84Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007)
"Data from ten patients with sarcoidosis treated with thalidomide between January 1998 and March 1999 were collected from delivery authorizations and analyzed."3.71[Sarcoidosis: thalidomide treatment in ten patients]. ( Bressieux, JM; Cosnes, A; Estines, O; Revuz, J; Roujeau, JC; Wolkenstein, P, 2001)
"A patient with sarcoidosis was treated with thalidomide for disfiguring and painful steroid unresponsive sarcoidal granulomas of the skin."3.70Disfiguring cutaneous manifestation of sarcoidosis treated with thalidomide: a case report. ( Koblenzer, PS; Lee, JB, 1998)
" Because administration of low doses of thalidomide has been successful in treating other inflammatory diseases, it was used in a patient with systemic sarcoidosis who was unresponsive to corticosteroids and in a patient with pulmonary sarcoidosis, in whom Kaposi's sarcoma developed after a course of corticosteroid therapy."3.69Treatment of cutaneous and pulmonary sarcoidosis with thalidomide. ( Bonaccorsi, P; Calvieri, S; Carlesimo, M; Giustini, S; Rossi, A, 1995)
"Sarcoidosis is a systemic granulomatous disease that affects numerous organs, commonly manifesting at the lungs and skin."2.52TNF-α: a treatment target or cause of sarcoidosis? ( Amber, KT; Bloom, R; Hertl, M; Mrowietz, U, 2015)
"Thalidomide was initially approved by the U."2.46Thalidomide and analogues: potential for immunomodulation of inflammatory and neoplastic dermatologic disorders. ( Ladizinski, B; Levis, WR; Sanchez, MR; Shannon, EJ, 2010)
"Thalidomide was developed in the 1950s as a sedative drug and withdrawn in 1961 because of its teratogenic effects, but has been rediscovered as an immuno-modulatory drug."2.46[Thalidomide as immunomodulatory drug: pharmacological actions and its indications]. ( Yasui, K, 2010)
"Thalidomide was first introduced in the 1950s as a sedative but was quickly removed from the market after it was linked to cases of severe birth defects."2.43Thalidomide: dermatological indications, mechanisms of action and side-effects. ( Hsu, S; Huang, DB; Pang, KR; Tyring, SK; Wu, JJ, 2005)
"Thalidomide has a different toxicity profile than corticosteroids or immunosuppressives."2.42Newer therapies for cutaneous sarcoidosis: the role of thalidomide and other agents. ( Baughman, RP; Lower, EE, 2004)
"Thalidomide was given to 2 patients with EOS (a 16-year-old girl and an 8-year-old boy) at an initial dosage of 2 mg/kg/day, and the dosage was increased if necessary."1.36Thalidomide dramatically improves the symptoms of early-onset sarcoidosis/Blau syndrome: its possible action and mechanism. ( Manki, A; Morishima, T; Takemoto, K; Tsuge, M; Yamamoto, M; Yashiro, M; Yasui, K, 2010)
"Thalidomide is an immunomodulatory agent that acts to inhibit production of tumor-necrosis factor-alpha (TNF-alpha), an important mediator in CNS inflammation, by enhancing TNF-alpha mRNA degradation."1.34Thalidomide for acute treatment of neurosarcoidosis. ( Hammond, ER; Kaplin, AI; Kerr, DA, 2007)
"Thalidomide was effective for muscular, cutaneous, and pulmonary involvement in our patient."1.32Successful treatment of muscle sarcoidosis with thalidomide. ( Lochmüller, H; Meindl, T; Müller-Felber, W; Schlotter-Weigel, B; Walter, MC, 2003)
"Our data suggest that thalidomide treatment of sarcoidosis results in granuloma differentiation to a Th1-type cellular immune response usually associated with protective immunity to tuberculosis and tuberculoid leprosy."1.31Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement. ( Kaplan, G; Kikuchi, T; Krueger, JG; Oliver, SJ, 2002)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.33)18.7374
1990's5 (13.89)18.2507
2000's16 (44.44)29.6817
2010's11 (30.56)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Wang, W2
Zhong, LQ1
Li, WD1
Wu, SJ1
Song, HM1
Droitcourt, C1
Rybojad, M2
Porcher, R1
Juillard, C1
Cosnes, A2
Joly, P1
Lacour, JP1
D'Incan, M1
Dupin, N1
Sassolas, B1
Misery, L1
Chevrant-Breton, J1
Lebrun-Vignes, B1
Desseaux, K1
Valeyre, D1
Revuz, J2
Tazi, A1
Chosidow, O1
Dupuy, A2
Huddleston, SM1
Houser, KH1
Walton, RC1
Amber, KT1
Bloom, R1
Mrowietz, U1
Hertl, M1
Xiong, X1
Ling, Y1
Yang, K1
Sun, W1
Su, Z1
Lu, Y1
Antoniu, SA1
Yasui, K2
Yashiro, M1
Tsuge, M1
Manki, A1
Takemoto, K1
Yamamoto, M1
Morishima, T1
Ladizinski, B1
Shannon, EJ1
Sanchez, MR1
Levis, WR1
Ahn, SW1
Kim, KT1
Youn, YC1
Kwon, OS1
Kim, YB1
Baughman, RP4
Judson, MA2
Ingledue, R1
Craft, NL1
Lower, EE3
Fazzi, P1
Manni, E1
Cristofani, R1
Cei, G1
Piazza, S1
Calabrese, R1
Antonelli, A1
Siciliano, G1
Barachini, P1
Carpi, A1
Teirstein, AS1
Moller, DR2
Lynch, JP1
Walter, MC1
Lochmüller, H1
Schlotter-Weigel, B1
Meindl, T1
Müller-Felber, W1
Vizel', AA1
Guryleva, ME1
Vizel', EA1
Nasretdinova, GP1
Nguyen, YT1
Cordoliani, F1
Vignon-Pennamen, MD1
Lebbé, C1
Morel, P1
Wu, JJ1
Huang, DB1
Pang, KR1
Hsu, S1
Tyring, SK1
Badgwell, C1
Rosen, T1
Hammond, ER1
Kaplin, AI1
Kerr, DA1
Barriere, H1
Prigent, F1
Ouazzani, W1
Carlesimo, M1
Giustini, S1
Rossi, A1
Bonaccorsi, P1
Calvieri, S1
Rousseau, L1
Beylot-Barry, M1
Doutre, MS1
Beylot, C1
Grasland, A1
Pouchot, J1
Chaumaizière, D1
Aitken, G1
Vinceneux, P1
Lee, JB1
Koblenzer, PS1
Saano, V1
Moraes, M1
Russo, G1
Estines, O1
Wolkenstein, P1
Bressieux, JM1
Roujeau, JC1
Hoch, O1
Müller, S1
Büttner, G1
Mensing, H2
Oliver, SJ1
Kikuchi, T1
Krueger, JG1
Kaplan, G1
Ochsendorf, F1
Kaufmann, R1
Picard, C1
Crickx, B1
Perron, J1
Lecerf, V1
Belaïch, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Controlled Trial of Thalidomide vs Placebo in Skin Sarcoidosis[NCT00305552]Phase 340 participants (Actual)Interventional2005-02-28Completed
The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis[NCT00794274]Phase 2/Phase 315 participants (Actual)Interventional2008-11-30Completed
Clinical Biomarkers of Disease Activity and Treatment Responses in Patients With CNS Sarcoidosis Treated With H.P. Acthar Gel[NCT02298491]Phase 44 participants (Actual)Interventional2016-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Total Number of Lesions

Total number of lesions assessed at 1 year (NCT02298491)
Timeframe: 1 year

Interventionlesions (Number)
H.P. Acthar Gel5

Reviews

13 reviews available for thalidomide and Besnier-Boeck Disease

ArticleYear
TNF-α: a treatment target or cause of sarcoidosis?
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:11

    Topics: Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Etanercept; Granuloma; Hum

2015
Targeting the TNF-alpha pathway in sarcoidosis.
    Expert opinion on therapeutic targets, 2010, Volume: 14, Issue:1

    Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Eta

2010
Thalidomide and analogues: potential for immunomodulation of inflammatory and neoplastic dermatologic disorders.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:7

    Topics: Behcet Syndrome; Dermatitis; Erythema Nodosum; Humans; Immunomodulation; Lupus Erythematosus, Cutane

2010
[Thalidomide as immunomodulatory drug: pharmacological actions and its indications].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2010, Volume: 33, Issue:5

    Topics: Behcet Syndrome; Child; Female; Humans; Immunologic Factors; Male; NF-kappa B; Sarcoidosis; Thalidom

2010
Treatment of sarcoidosis -- from a basic science point of view.
    Journal of internal medicine, 2003, Volume: 253, Issue:1

    Topics: Etanercept; Granuloma; Humans; Immunoglobulin G; Immunosuppressive Agents; Interleukins; Pentoxifyll

2003
Difficult treatment issues in sarcoidosis.
    Journal of internal medicine, 2003, Volume: 253, Issue:1

    Topics: Antibodies, Monoclonal; Antimalarials; Azathioprine; Cyclophosphamide; Decision Making; Humans; Immu

2003
[The role of tumor necrosis factor in pathogenesis and treatment of sarcoidosis].
    Klinicheskaia meditsina, 2003, Volume: 81, Issue:9

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Humans; Immunosuppressive Agents; Infliximab; Sarcoido

2003
Newer therapies for cutaneous sarcoidosis: the role of thalidomide and other agents.
    American journal of clinical dermatology, 2004, Volume: 5, Issue:6

    Topics: Chronic Disease; Clinical Trials as Topic; Facial Dermatoses; Humans; Immunosuppressive Agents; Sarc

2004
Thalidomide: dermatological indications, mechanisms of action and side-effects.
    The British journal of dermatology, 2005, Volume: 153, Issue:2

    Topics: Adult; Behcet Syndrome; Dermatologic Agents; Erythema; Graft vs Host Disease; Histiocytosis, Langerh

2005
Cutaneous sarcoidosis therapy updated.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents

2007
[New therapeutic application of thalidomide].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:7

    Topics: Autoimmune Diseases; Colitis, Ulcerative; Erythema Multiforme; Female; Histiocytosis; Humans; Immuno

1996
Thalidomide and its dermatologic uses.
    The American journal of the medical sciences, 2001, Volume: 321, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Behcet Syndrome; Dermatologic Agents; Erythema Nodosum; Facial D

2001
[Florid cutaneous sarcoidosis. Therapeutic difficulties].
    Annales de dermatologie et de venereologie, 1989, Volume: 116, Issue:11

    Topics: Adrenal Cortex Hormones; Cyclosporins; Facial Dermatoses; Humans; Male; Middle Aged; PUVA Therapy; S

1989

Trials

5 trials available for thalidomide and Besnier-Boeck Disease

ArticleYear
A randomized, investigator-masked, double-blind, placebo-controlled trial on thalidomide in severe cutaneous sarcoidosis.
    Chest, 2014, Volume: 146, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Female; France; Humans; Immunosuppressive Agents; Male; Middle Age

2014
Efficacy and safety of apremilast in chronic cutaneous sarcoidosis.
    Archives of dermatology, 2012, Volume: 148, Issue:2

    Topics: Female; Humans; Male; Phosphodiesterase 4 Inhibitors; Sarcoidosis; Severity of Illness Index; Skin D

2012
Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:4

    Topics: Adult; Aged; Contraindications; Dose-Response Relationship, Drug; Drug Resistance; Feasibility Studi

2012
Thalidomide for chronic sarcoidosis.
    Chest, 2002, Volume: 122, Issue:1

    Topics: Adult; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents;

2002
Treatment of cutaneous sarcoidosis with thalidomide.
    Journal of the American Academy of Dermatology, 2004, Volume: 50, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Male; Middle Aged

2004

Other Studies

18 other studies available for thalidomide and Besnier-Boeck Disease

ArticleYear
Thalidomide may be an effective drug for Blau syndrome: a case report.
    Annals of palliative medicine, 2022, Volume: 11, Issue:7

    Topics: Arthritis; Female; Humans; Nod2 Signaling Adaptor Protein; Sarcoidosis; Synovitis; Thalidomide; Uvei

2022
Thalidomide for recalcitrant nodular scleritis in sarcoidosis.
    JAMA ophthalmology, 2014, Volume: 132, Issue:11

    Topics: Female; Humans; Immunosuppressive Agents; Middle Aged; Recurrence; Sarcoidosis; Scleritis; Thalidomi

2014
Case of sarcoidosis presenting with symmetrical facial keratotic papules.
    The Journal of dermatology, 2018, Volume: 45, Issue:2

    Topics: Cheek; Female; Hepatic Duct, Common; Humans; Keratosis; Lymph Nodes; Lymphadenopathy; Middle Aged; S

2018
Thalidomide dramatically improves the symptoms of early-onset sarcoidosis/Blau syndrome: its possible action and mechanism.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:1

    Topics: Adolescent; Arthrography; Cells, Cultured; Child; Cytokines; Female; Humans; Immunosuppressive Agent

2010
Isolated spinal cord neurosarcoidosis diagnosed by cord biopsy and thalidomide trial.
    Journal of Korean medical science, 2011, Volume: 26, Issue:1

    Topics: Adrenal Cortex Hormones; Biopsy; Central Nervous System Diseases; Female; Humans; Immunosuppressive

2011
Successful treatment of muscle sarcoidosis with thalidomide.
    Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2003, Volume: 22, Issue:1

    Topics: Adult; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Muscular Diseases; Sarcoi

2003
Thalidomide for acute treatment of neurosarcoidosis.
    Spinal cord, 2007, Volume: 45, Issue:12

    Topics: Adult; Brain; Granuloma; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Proprio

2007
[Cutaneous sarcoidosis. Treatment with thalidomide].
    Presse medicale (Paris, France : 1983), 1983, Apr-02, Volume: 12, Issue:15

    Topics: Humans; Sarcoidosis; Skin Diseases; Thalidomide

1983
[Cutaneous sarcoidosis. Treatment with thalidomide].
    Presse medicale (Paris, France : 1983), 1983, Dec-24, Volume: 12, Issue:47

    Topics: Humans; Leg Ulcer; Sarcoidosis; Thalidomide

1983
Treatment of cutaneous and pulmonary sarcoidosis with thalidomide.
    Journal of the American Academy of Dermatology, 1995, Volume: 32, Issue:5 Pt 2

    Topics: Aged; Female; Humans; Middle Aged; Sarcoidosis; Sarcoidosis, Pulmonary; Sarcoma, Kaposi; Skin Diseas

1995
Cutaneous sarcoidosis successfully treated with low doses of thalidomide.
    Archives of dermatology, 1998, Volume: 134, Issue:8

    Topics: Adult; Cicatrix; Female; Fibrosis; Humans; Immunosuppressive Agents; Sarcoidosis; Skin Diseases; Tha

1998
[Effectiveness of thalidomide treatment during cutaneous sarcoidosis].
    La Revue de medecine interne, 1998, Volume: 19, Issue:3

    Topics: Dermatologic Agents; Female; Humans; Middle Aged; Sarcoidosis; Skin Diseases; Thalidomide; Treatment

1998
Disfiguring cutaneous manifestation of sarcoidosis treated with thalidomide: a case report.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:5 Pt 2

    Topics: Dermatologic Agents; Drug Administration Schedule; Facial Dermatoses; Female; Fingers; Glucocorticoi

1998
[Sarcoidosis: thalidomide treatment in ten patients].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:5

    Topics: Chronic Disease; Dermatologic Agents; Drug Administration Schedule; Humans; Immunosuppressive Agents

2001
[Thalidomide in the treatment of cutaneous and systemic sarcoidosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2001, Volume: 52, Issue:10 Pt 2

    Topics: Adult; Dermatologic Agents; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Male; Middle

2001
Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement.
    Clinical immunology (Orlando, Fla.), 2002, Volume: 102, Issue:3

    Topics: Adult; Antigens, CD; Dendritic Cells; Dermatologic Agents; Female; Flow Cytometry; HLA-DR Antigens;

2002
[New indication for thalidomide?].
    Deutsche medizinische Wochenschrift (1946), 2002, Apr-12, Volume: 127, Issue:15

    Topics: Humans; Immunosuppressive Agents; Sarcoidosis; Thalidomide

2002
[Comment on O. Hoch et al.: "Thalidomide in treatment of cutaneous and systemic sarcoidosis"].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2002, Volume: 53, Issue:2

    Topics: Humans; Sarcoidosis; Skin Diseases; Thalidomide; Treatment Outcome

2002