thalidomide has been researched along with Benign Psychomotor Epilepsy, Childhood in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility of epilepsy resulting from maternal thalidomide ingestion was investigated by obtaining a telephoned neurological history from all suspect families in the United Kingdom in which the specific diagnosis was uncertain." | 7.65 | Epilepsy: a neurological complication of thalidomide embryopathy. ( Stephenson, JB, 1976) |
| "Thalidomide (TAL) has shown potential therapeutic effects in neurological diseases like epilepsy." | 5.91 | Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model. ( Cumbres-Vargas, IM; Pichardo-Macías, LA; Ramírez-San Juan, E; Zamudio, SR, 2023) |
| "The possibility of epilepsy resulting from maternal thalidomide ingestion was investigated by obtaining a telephoned neurological history from all suspect families in the United Kingdom in which the specific diagnosis was uncertain." | 3.65 | Epilepsy: a neurological complication of thalidomide embryopathy. ( Stephenson, JB, 1976) |
| "Thalidomide (TAL) has shown potential therapeutic effects in neurological diseases like epilepsy." | 1.91 | Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model. ( Cumbres-Vargas, IM; Pichardo-Macías, LA; Ramírez-San Juan, E; Zamudio, SR, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cumbres-Vargas, IM | 1 |
| Zamudio, SR | 1 |
| Pichardo-Macías, LA | 1 |
| Ramírez-San Juan, E | 1 |
| Ashhab, MU | 1 |
| Omran, A | 1 |
| Kong, H | 1 |
| Gan, N | 1 |
| He, F | 1 |
| Peng, J | 1 |
| Yin, F | 1 |
| Stephenson, JB | 1 |
3 other studies available for thalidomide and Benign Psychomotor Epilepsy, Childhood
| Article | Year |
|---|---|
Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model.
Topics: Animals; Disease Models, Animal; Encephalitis; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Male; | 2023 |
Expressions of tumor necrosis factor alpha and microRNA-155 in immature rat model of status epilepticus and children with mesial temporal lobe epilepsy.
Topics: Adolescent; Animals; Astrocytes; Case-Control Studies; Child; Epilepsy, Temporal Lobe; Female; Hippo | 2013 |
Epilepsy: a neurological complication of thalidomide embryopathy.
Topics: Adolescent; Ear; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; Heart Defects, C | 1976 |