thalidomide has been researched along with Autosomal Recessive Chronic Granulomatous Disease in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has a favorable safety profile compared with other alternatives and could be considered a feasible therapeutic option for this type of condition in selected patients." | 5.43 | Chronic Recurrent Multifocal Osteomyelitis and Thalidomide in Chronic Granulomatous Disease. ( Barber, I; Fernández-Polo, A; Fontecha, CG; Martín-Nalda, A; Martinez-Gallo, M; Roca, I; Soler-Palacin, P, 2016) |
| "Thalidomide has a favorable safety profile compared with other alternatives and could be considered a feasible therapeutic option for this type of condition in selected patients." | 1.43 | Chronic Recurrent Multifocal Osteomyelitis and Thalidomide in Chronic Granulomatous Disease. ( Barber, I; Fernández-Polo, A; Fontecha, CG; Martín-Nalda, A; Martinez-Gallo, M; Roca, I; Soler-Palacin, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawai, T | 2 |
| Watanabe, N | 1 |
| Yokoyama, M | 1 |
| Arai, K | 1 |
| Oana, S | 1 |
| Harayama, S | 1 |
| Yasui, K | 1 |
| Oh-Ishi, T | 1 |
| Onodera, M | 1 |
| Noel, N | 1 |
| Mahlaoui, N | 1 |
| Blanche, S | 2 |
| Suarez, F | 2 |
| Coignard-Biehler, H | 1 |
| Durieu, I | 1 |
| Godeberge, P | 1 |
| Sokol, H | 2 |
| Catherinot, E | 1 |
| Poiree, S | 1 |
| Chapdelaine, H | 1 |
| Dunogue, B | 1 |
| Bodemer, C | 1 |
| Lecuit, M | 1 |
| Fischer, A | 1 |
| Lortholary, O | 1 |
| Hermine, O | 2 |
| Martín-Nalda, A | 1 |
| Roca, I | 1 |
| Fontecha, CG | 1 |
| Fernández-Polo, A | 1 |
| Barber, I | 1 |
| Martinez-Gallo, M | 1 |
| Soler-Palacin, P | 1 |
| Meatchi, T | 1 |
| Malamut, G | 1 |
| Pocidalo, MA | 1 |
| Cellier, C | 1 |
| Aguilera, DG | 1 |
| Tomita, T | 1 |
| Rajaram, V | 1 |
| Fangusaro, J | 1 |
| Katz, BZ | 1 |
| Shulman, S | 1 |
| Goldman, S | 1 |
1 review available for thalidomide and Autosomal Recessive Chronic Granulomatous Disease
| Article | Year |
|---|---|
[A therapeutic approach towards chronic granulomatous disease].
Topics: Cytokines; Genetic Therapy; Genetic Vectors; Granulomatous Disease, Chronic; Hematopoietic Stem Cell | 2014 |
5 other studies available for thalidomide and Autosomal Recessive Chronic Granulomatous Disease
| Article | Year |
|---|---|
Thalidomide attenuates excessive inflammation without interrupting lipopolysaccharide-driven inflammatory cytokine production in chronic granulomatous disease.
Topics: Adenosine Triphosphate; Caspase 1; Cells, Cultured; Child, Preschool; Cytokines; Granulomatous Disea | 2013 |
Efficacy and safety of thalidomide in patients with inflammatory manifestations of chronic granulomatous disease: a retrospective case series.
Topics: Adolescent; Child; Child, Preschool; Female; Granulomatous Disease, Chronic; Humans; Immunosuppressi | 2013 |
Chronic Recurrent Multifocal Osteomyelitis and Thalidomide in Chronic Granulomatous Disease.
Topics: Child; Granulomatous Disease, Chronic; Humans; Immunosuppressive Agents; Male; Osteomyelitis; Radion | 2016 |
Thalidomide as a treatment for refractory CGD colitis.
Topics: Biopsy; Colitis; Diagnosis, Differential; Follow-Up Studies; Granulomatous Disease, Chronic; Humans; | 2009 |
Glioblastoma multiforme in a patient with chronic granulomatous disease treated with subtotal resection, radiation, and thalidomide: case report of a long-term survivor.
Topics: Adolescent; Brain Neoplasms; Combined Modality Therapy; Craniotomy; Diagnosis, Differential; Female; | 2009 |