thalidomide has been researched along with Autosomal Chromosome Disorders in 24 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Present knowledge of chromosomal aberrations associated with microphthalmia is surveyed, and some of the syndromes and phenocopies in the mentally retarded in which microphthalmia may be found are reviewed." | 2.35 | The heterogeneity of microphthalmia in the mentally retarded. ( Warburg, M, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biran, N | 1 |
| Jagannath, S | 1 |
| Chari, A | 1 |
| Neemat, K | 1 |
| Rania, K | 1 |
| Tarek, M | 1 |
| Hamdy, AA | 1 |
| BENDA, CE | 1 |
| BAUGHMAN, FA | 1 |
| YANZON, NA | 1 |
| RODRIGUEZDEAGNESE, LR | 1 |
| GIACOMELLO, G | 1 |
| MALATESTA, P | 1 |
| QUAGLIA, G | 1 |
| JENSEN, MK | 1 |
| Fassas, AB | 1 |
| Muwalla, F | 1 |
| Berryman, T | 1 |
| Benramdane, R | 1 |
| Joseph, L | 1 |
| Anaissie, E | 1 |
| Sethi, R | 1 |
| Desikan, R | 1 |
| Siegel, D | 1 |
| Badros, A | 1 |
| Toor, A | 1 |
| Zangari, M | 1 |
| Morris, C | 1 |
| Angtuaco, E | 1 |
| Mathew, S | 1 |
| Wilson, C | 1 |
| Hough, A | 1 |
| Harik, S | 1 |
| Barlogie, B | 1 |
| Tricot, G | 1 |
| Bohm, R | 1 |
| Nitsch, K | 1 |
| Achs, R | 1 |
| Harper, RG | 1 |
| Shiono, H | 1 |
| Jörgensen, G | 3 |
| Shapiro, IuL | 1 |
| Vaĭntrub, MIa | 1 |
| Grinberg, KN | 1 |
| Zhurkov, VS | 1 |
| Holt, SB | 1 |
| Kelsey, FO | 1 |
| Kernis, MM | 1 |
| Kucera, J | 1 |
| Shakibi, JG | 1 |
| Watanabe, G | 1 |
| Warburg, M | 1 |
| Sax, K | 1 |
| Sax, HJ | 1 |
| Hirth, L | 1 |
| Döser, R | 1 |
| Gordon, H | 1 |
10 reviews available for thalidomide and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Risk stratification in multiple myeloma, part 2: the significance of genetic risk factors in the era of currently available therapies.
Topics: Angiogenesis Inhibitors; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 13; Chr | 2013 |
Myeloma of the central nervous system: association with high-risk chromosomal abnormalities, plasmablastic morphology and extramedullary manifestations.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms | 2002 |
Dermatoglyphics.
Topics: Abnormalities, Drug-Induced; Anemia, Sickle Cell; Anencephaly; Cerebral Palsy; Chromosome Aberration | 1968 |
[Diseases and dermatoglyphics].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Chromosome Aberrations; Chromo | 1970 |
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent | 1972 |
Drugs in pregnancy and their effects on pre- and postnatal development.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Anticonvulsants; Antimetabolites; Central N | 1973 |
Principles of teratology.
Topics: Abnormalities, Drug-Induced; Amniocentesis; Animals; Chromosome Aberrations; Chromosome Disorders; C | 1972 |
Etiology of congenital heart disease.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Chromosome Aberrations; Chromosome Disorders; | 1969 |
[Experimental epidemiology].
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Cleft Palate; Congenital Abnormalities; Diabe | 1971 |
The heterogeneity of microphthalmia in the mentally retarded.
Topics: Abnormalities, Multiple; Abortifacient Agents; Adolescent; Adult; Brain Injuries; Child, Preschool; | 1971 |
14 other studies available for thalidomide and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Effect of 13q deletion on IL-6 production in patients with multiple myeloma: a hypothesis may hold true.
Topics: Adult; Aged; Antineoplastic Agents; Boronic Acids; Bortezomib; Case-Control Studies; Chromosome Dele | 2014 |
[AN UNUSUAL CASE OF DEVELOPMENTAL DISORDER--PROBABLY BASED ON PRENATAL THALIDOMIDE DAMAGE, WITH CHROMOSOMAL ANALYSIS].
Topics: Abnormalities, Drug-Induced; Child; Chromosome Aberrations; Chromosome Disorders; Developmental Disa | 1963 |
[COMMENTARIES ABOUT 107 CONGENITAL MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Aminopterin; Chromosome Aberrations; Chromosome Disorders; Congenital A | 1963 |
ACTION OF THALIDOMIDE ON RADICAL MERISTEMS OF ALLIUM CEPA.
Topics: Cell Division; Chromosome Aberrations; Chromosome Disorders; Meristem; Onions; Pharmacology; Plants; | 1964 |
CHROMOSOME ABERRATIONS IN HUMAN CELLS INDUCED BY THALIDOMIDE IN VITRO: PRELIMINARY REPORT.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; In Vitro Techniques; Lymphocytes; Pharmac | 1965 |
Another chance for thalidomide?
Topics: Abnormalities, Drug-Induced; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Culture | 1966 |
[Abnormalities in the field of otorhinolaryngology. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Chromosome Aberrations | 1972 |
[Malformations in otorhinolaryngology. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Chromosome Aberrations; Chromosome Diso | 1972 |
[Genetic analysis of skeletal diseases. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Bone Diseases; Child; Chromoso | 1973 |
The significance of dermatoglyphics in medicine. A short survey and summary.
Topics: Abnormalities, Drug-Induced; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15 | 1973 |
Prospects and limitations of epidemiology in human teratology.
Topics: Abnormalities, Drug-Induced; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Congenital A | 1973 |
Radiomimetic beverages, drugs, and mutagens.
Topics: Antiemetics; Benzamides; Beverages; Chromosome Aberrations; Chromosome Disorders; Coffee; Cyclizine; | 1966 |
[Skin ridges and skin furrows in dysmelia].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Chromosome Aberration | 1970 |
Genetical, social, and medical aspects of abortion.
Topics: Abnormalities, Drug-Induced; Abortion, Criminal; Abortion, Legal; Abortion, Therapeutic; Adolescent; | 1968 |