thalidomide has been researched along with Autoimmune Thyroiditis in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary hypothyroidism is the most common side effect, although thyrotoxicosis and effects on thyroid-stimulating hormone secretion and thyroid hormone metabolism have also been described." | 2.47 | Thyroid dysfunction from antineoplastic agents. ( Hamnvik, OP; Larsen, PR; Marqusee, E, 2011) |
| "Autoimmune diseases are prevalent among MDS patients." | 1.43 | Autoimmune diseases and myelodysplastic syndromes. ( Al Ali, NH; Bart-Smith, E; Craig, BM; Epling-Burnette, PK; Komrokji, RS; Kordasti, S; Kulasekararaj, A; Lancet, JE; List, AF; Mufti, GJ; Padron, E; Pinilla-Ibarz, J; Zhang, L, 2016) |
| "Thalidomide did not suppress the incidence of lymphocytic thyroiditis and serum anti-thyroglobulin antibodies or affect the serum concentrations of T4, T3 and TSH in this rat model." | 1.28 | Effect of thalidomide on the incidence of iodine-induced and spontaneous lymphocytic thyroiditis and spontaneous diabetes mellitus in the BB/Wor rat. ( Abend, S; Alex, S; Appel, MC; Braverman, LE; Lueprasitsakul, W; Reinhardt, W, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Komrokji, RS | 1 |
| Kulasekararaj, A | 1 |
| Al Ali, NH | 1 |
| Kordasti, S | 1 |
| Bart-Smith, E | 1 |
| Craig, BM | 1 |
| Padron, E | 1 |
| Zhang, L | 1 |
| Lancet, JE | 1 |
| Pinilla-Ibarz, J | 1 |
| List, AF | 1 |
| Mufti, GJ | 1 |
| Epling-Burnette, PK | 1 |
| Hamnvik, OP | 1 |
| Larsen, PR | 1 |
| Marqusee, E | 1 |
| Erdem, F | 1 |
| Gundogdu, M | 1 |
| Kiki, I | 1 |
| Capoĝlu, I | 1 |
| Lueprasitsakul, W | 1 |
| Abend, S | 1 |
| Alex, S | 1 |
| Reinhardt, W | 1 |
| Appel, MC | 1 |
| Braverman, LE | 1 |
1 review available for thalidomide and Autoimmune Thyroiditis
| Article | Year |
|---|---|
Thyroid dysfunction from antineoplastic agents.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antica | 2011 |
3 other studies available for thalidomide and Autoimmune Thyroiditis
| Article | Year |
|---|---|
Autoimmune diseases and myelodysplastic syndromes.
Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azacitidine; Comorbidity; Disease Progression; | 2016 |
Autoimmune thyroiditis during thalidomide treatment.
Topics: Autoantibodies; Female; Humans; Iodide Peroxidase; Middle Aged; Multiple Myeloma; Thalidomide; Thyro | 2006 |
Effect of thalidomide on the incidence of iodine-induced and spontaneous lymphocytic thyroiditis and spontaneous diabetes mellitus in the BB/Wor rat.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Iodine; Male; Rats; Rat | 1990 |