thalidomide has been researched along with Auditory Hyperesthesia in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Auditory hypersensitivity in autism is frequently observed in clinics." | 5.56 | Altered neuronal activity in the auditory brainstem following sound stimulation in thalidomide-induced autism model rats. ( Ida-Eto, M; Narita, M; Noro, Y; Ohkawara, T; Tsugiyama, LE, 2020) |
| "Autism model rats were prepared by prenatal exposure to thalidomide on embryonic day 9 and 10 in pregnant rats." | 3.85 | Mechanism of auditory hypersensitivity in human autism using autism model rats. ( Hara, N; Ida-Eto, M; Narita, M; Ohkawara, T, 2017) |
| "Auditory hypersensitivity in autism is frequently observed in clinics." | 1.56 | Altered neuronal activity in the auditory brainstem following sound stimulation in thalidomide-induced autism model rats. ( Ida-Eto, M; Narita, M; Noro, Y; Ohkawara, T; Tsugiyama, LE, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsugiyama, LE | 1 |
| Ida-Eto, M | 2 |
| Ohkawara, T | 2 |
| Noro, Y | 1 |
| Narita, M | 2 |
| Hara, N | 1 |
2 other studies available for thalidomide and Auditory Hyperesthesia
| Article | Year |
|---|---|
Altered neuronal activity in the auditory brainstem following sound stimulation in thalidomide-induced autism model rats.
Topics: Acoustic Stimulation; Animals; Autistic Disorder; Brain Stem; Female; Hyperacusis; Immunosuppressive | 2020 |
Mechanism of auditory hypersensitivity in human autism using autism model rats.
Topics: Animals; Auditory Pathways; Auditory Perception; Autism Spectrum Disorder; Autistic Disorder; Hypera | 2017 |