thalidomide has been researched along with Atrophy, Muscle in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Exercise is safe and has physiologic benefits for patients undergoing MM treatment; exercise combined with epoetin alfa helped alleviate anemia." | 5.16 | Effects of exercise on fatigue, sleep, and performance: a randomized trial. ( Anaissie, EJ; Coleman, EA; Coon, SK; Enderlin, C; Goodwin, JA; Kennedy, R; Lockhart, K; McNatt, P; Richards, K; Stewart, CB, 2012) |
| "In patients with advanced cancer, AIDS and end-stage organ diseases, symptoms of cachexia syndrome include decrease in appetite, weight loss, decreased performance status, and an increase in the systemic inflammatory response." | 2.50 | Immunomodulatory agents for the treatment of cachexia. ( Bhargava, R; Chasen, M; Hirschman, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chasen, M | 1 |
| Bhargava, R | 1 |
| Hirschman, S | 1 |
| Coleman, EA | 1 |
| Goodwin, JA | 1 |
| Kennedy, R | 1 |
| Coon, SK | 1 |
| Richards, K | 1 |
| Enderlin, C | 1 |
| Stewart, CB | 1 |
| McNatt, P | 1 |
| Lockhart, K | 1 |
| Anaissie, EJ | 1 |
| Vescovo, G | 1 |
| Ravara, B | 1 |
| Angelini, A | 1 |
| Sandri, M | 1 |
| Carraro, U | 1 |
| Ceconi, C | 1 |
| Dalla Libera, L | 1 |
| Argilés, JM | 1 |
| Busquets, S | 1 |
| López-Soriano, FJ | 1 |
| Fotopulos, D | 1 |
| Shiono, H | 1 |
| Seitelberger, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Initiated Individualized Physical Training in Newly Diagnosed Multiple Myeloma Patients; Effects on Physical Function, Physical Activity, Quality of Life, Pain, and Bone Disease.[NCT02439112] | 102 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Patients With Anorexia Associated With Advanced Lung Cancer: Randomized Double Blind Clinical Trial[NCT02802540] | Phase 2/Phase 3 | 78 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thalidomide and Atrophy, Muscle
| Article | Year |
|---|---|
Immunomodulatory agents for the treatment of cachexia.
Topics: Adipose Tissue; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Appetite; C-Reacti | 2014 |
The pivotal role of cytokines in muscle wasting during cancer.
Topics: Animals; Anorexia; Antibodies; Cachexia; Cytokines; Humans; Models, Biological; Muscle, Skeletal; Mu | 2005 |
[Diseases and dermatoglyphics].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Chromosome Aberrations; Chromo | 1970 |
1 trial available for thalidomide and Atrophy, Muscle
| Article | Year |
|---|---|
Effects of exercise on fatigue, sleep, and performance: a randomized trial.
Topics: Adult; Affect; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 2012 |
3 other studies available for thalidomide and Atrophy, Muscle
| Article | Year |
|---|---|
Effect of thalidomide on the skeletal muscle in experimental heart failure.
Topics: Animals; Apoptosis; Heart Failure; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy C | 2002 |
[Huntington's chorea and chronic-progressive spinal muscular atrophy].
Topics: Adult; Anxiety; Arm; Chronic Disease; Female; Functional Laterality; Humans; Huntington Disease; Men | 1966 |
[Thalidomide polyneuropathy. Clinical bioptical studies].
Topics: Electromyography; Female; Humans; Middle Aged; Muscular Atrophy; Polyneuropathies; Thalidomide | 1968 |