Page last updated: 2024-11-05

thalidomide and Atherogenesis

thalidomide has been researched along with Atherogenesis in 4 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Apremilast is a new anti-inflammatory drug that possesses a potential anti-atherosclerosis effect."5.72Protective roles of apremilast via Sirtuin 1 in atherosclerosis. ( Sui, D; Yu, H, 2022)
"Apremilast is a new anti-inflammatory drug that possesses a potential anti-atherosclerosis effect."1.72Protective roles of apremilast via Sirtuin 1 in atherosclerosis. ( Sui, D; Yu, H, 2022)
"Attenuated inflammation and pathological angiogenesis achieved in hypercholesterolemia by thalidomide are accompanied by restoration of renovascular endothelial function but decreased basal renal hemodynamics."1.34Role of renal cortical neovascularization in experimental hypercholesterolemia. ( Chade, AR; Galili, O; Krier, JD; Lerman, A; Lerman, LO, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Sui, D1
Yu, H1
Kampschulte, M1
Gunkel, I1
Stieger, P1
Sedding, DG1
Brinkmann, A1
Ritman, EL1
Krombach, GA1
Langheinrich, AC1
Ismail, B1
Aboul-Fotouh, S1
Mansour, AA1
Shehata, HH1
Salman, MI1
Ibrahim, EA1
Hassan, OA1
Abdel-tawab, AM1
Chade, AR1
Krier, JD1
Galili, O1
Lerman, A1
Lerman, LO1

Other Studies

4 other studies available for thalidomide and Atherogenesis

ArticleYear
Protective roles of apremilast via Sirtuin 1 in atherosclerosis.
    Bioengineered, 2022, Volume: 13, Issue:5

    Topics: Atherosclerosis; Cholesterol; Humans; Scavenger Receptors, Class E; Sirtuin 1; Thalidomide

2022
Thalidomide influences atherogenesis in aortas of ApoE(-/-)/LDLR (-/-) double knockout mice: a nano-CT study.
    The international journal of cardiovascular imaging, 2014, Volume: 30, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Aorta; Aortic Diseases; Aortography; Apolipoproteins E; Atheroscle

2014
Behavioural, metabolic, and endothelial effects of the TNF-α suppressor thalidomide on rats subjected to chronic mild stress and fed an atherogenic diet.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:5

    Topics: Animals; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Atherosclerosis; Chronic Disease; Depres

2014
Role of renal cortical neovascularization in experimental hypercholesterolemia.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Atherosclerosis; Blood Pressure; Cell Proliferation; Disease Model

2007